Alpha shape theory for 3D visualization and volumetric measurement of brain tumor progression using magnetic resonance images
Alpha shape theory for 3D visualization and volumetric measurement of brain tumor progression using magnetic resonance images
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DOI：
10.1016/j.mri.2015.03.008
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发表时间：
2015-07-01
影响因子：
2.5
通讯作者：
Shuaib, Ibrahim Lutfi
中科院分区：
文献类型：
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作者：
Al-Tamimi, Mohammed Sabbih Hamoud;Sulong, Ghazali;Shuaib, Ibrahim Lutfi
脑肿瘤的切除是外科手术中一项棘手的任务，因为它直接影响患者的生存率。通过术前和术后磁共振成像（MRI）的体积和尺寸来确定肿瘤切除范围的完整信息需要准确的估计和比较。利用自主开发的软件，采用主动轮廓分割技术对术前磁共振图像上的脑肿瘤进行分割。通过α形状理论从肿瘤的轮廓中获得肿瘤体积。图形用户界面是为绘制、可视化和估计脑肿瘤的体积而开发的。利用互联网脑分割库数据集（IBSR）分析和确定肿瘤体积的可重复性和再现性。通过与金标准法的估算量比较，验证了该方法的准确性。利用活动轮廓分割技术可以检测出脑肿瘤的边界。此外，体积描述和可视化使肿瘤组织及其周围的交互式检查成为可能。我们的结果令人钦佩的特征表明，与其他现有的标准方法相比，alpha形状理论在精确测量肿瘤体积方面具有优势。(C) 2015爱思唯尔公司版权所有。
Resection of brain tumors is a tricky task in surgery due to its direct influence on the patients' survival rate. Determining the tumor resection extent for its complete information via-a-vis volume and dimensions in pre- and post-operative Magnetic Resonance Images (MRI) requires accurate estimation and comparison. The active contour segmentation technique is used to segment brain tumors on pre-operative MR images using self-developed software. Tumor volume is acquired from its contours via alpha shape theory. The graphical user interface is developed for rendering, visualizing and estimating the volume of a brain tumor. Internet Brain Segmentation Repository dataset (IBSR) is employed to analyze and determine the repeatability and reproducibility of tumor volume. Accuracy of the method is validated by comparing the estimated volume using the proposed method with that of gold-standard. Segmentation by active contour technique is found to be capable of detecting the brain tumor boundaries. Furthermore, the volume description and visualization enable an interactive examination of tumor tissue and its surrounding. Admirable features of our results demonstrate that alpha shape theory in comparison to other existing standard methods is superior for precise volumetric measurement of tumor. (C) 2015 Elsevier Inc. All rights reserved.