Rh(I)-catalyzed CO gas-free carbonylative cyclization of organic halides with tethered nucleophiles using aldehydes as a substitute for carbon monoxide
Rh(I)-catalyzed CO gas-free carbonylative cyclization of organic halides with tethered nucleophiles using aldehydes as a substitute for carbon monoxide
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DOI：
10.1016/j.jorganchem.2006.08.038
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发表时间：
2007-01-01
影响因子：
2.3
通讯作者：
Kakiuchi, Kiyomi
中科院分区：
文献类型：
--
作者：
Morimoto, Tsumoru;Fujioka, Masahiko;Kakiuchi, Kiyomi
有机卤化物的无CO气体羰基化环化，与拴住的氮、氧和碳亲核试剂，用醛作为一氧化碳的替代品，可以在铑络合物的催化量存在下实现。该反应包括铑催化剂使醛脱碳，以及利用原位形成的羰基铑连续羰基化有机卤化物。具有吸电子基团的醛具有更高的给予羰基部分的能力。(c) 2006 Elsevier B.V.版权所有
The CO gas-free carbonylative cyclization of organic halides, with tethered nitrogen, oxygen, and carbon nucleophiles, with aldehydes as a substitute for carbon monoxide can be achieved in the presence of a catalytic amount of a rhodium complex. The reaction involves the decarbonylation of the aldehyde by the rhodium catalyst, and the successive carbonylation of an organic halide utilizing the rhodium carbonyl that is formed in situ. Aldehydes having electron-withdrawing groups showed a higher ability to donate the carbonyl moiety. (c) 2006 Elsevier B.V. All rights reserved.