PROPERTIES OF CUTANEOUS TOUCH RECEPTORS IN CAT

PROPERTIES OF CUTANEOUS TOUCH RECEPTORS IN CAT
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DOI:
10.1113/jphysiol.1960.sp006520
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发表时间:
1960-01-01
影响因子:
5.5
通讯作者:
MCINTYRE, AK
MCINTYRE, AK
中科院分区:
医学1区
文献类型:
--
作者:
HUNT, CC;MCINTYRE, AK

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方法使用戊巴比妥钠(Nembutal; Abbott Laboratories)麻醉的成年猫。在腰骶区的椎板切除术后,暴露的脊髓和根用用95%O2和5%CO2平衡的石蜡油覆盖。L 6 ~ S2的背根和腹根在近脊髓处分开。通过在腘窝上切开一个切口,暴露腓肠神经,并将其完整地放置在石蜡油池中的刺激电极上。后肢和臀部的其他神经被切断。在背根的细丝中分离出单个传入纤维,用一个小珠状热敏电阻测量皮肤温度,该热敏电阻置于离所研究的感受器一定距离的皮下,然后穿过皮肤,直到它停留在离感受器几毫米处,指向皮肤。在这个位置,它在几秒钟内对皮肤温度的变化做出反应,
METHODS Adult cats anaesthetized with pentobarbital sodium (Nembutal; Abbott Laboratories) were used. After laminectomy in the lumbosacral region, the exposed spinal cord and roots were covered with paraffin oil equilibrated with 95% 02 and 5% CO2. Dorsal and ventral roots from L 6 to S 2 were divided near the cord. By an incision over the popliteal fossa the sural nerve was exposed and placed intact on stimulating electrodes in a pool of paraffin oil. Other nerves in the hindlimb and hip were cut. Single afferent fibres were isolated in filaments of dorsal root.Skin temperature was measured by a small bead thermistor introduced subcutaneously at some distancefrom the receptor under study and then passed under the skin until it rested a few millimetres from the receptor, pointing outwards against the skin. In this position it responded within a few seconds to changes in skin temperature produced by