Intracellular potentials of mammalian dorsal root ganglion cells.
Intracellular potentials of mammalian dorsal root ganglion cells.
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哺乳动物背根神经节细胞的细胞内电位。
DOI：
10.1152/jn.1961.24.6.569
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发表时间：
1961
影响因子：
2.5
通讯作者：
G. Austin
中科院分区：
文献类型：
--
作者：
M. Sato;G. Austin
在过去的十年里，随着Ling和Gerard(16)关于从单个肌肉细胞内记录的原始工作之后，记录细胞内电位的技术得到了极大的扩展。背根神经节细胞(以下简称DRG细胞)因其独特的解剖学和生理学特性而备受关注。此外，这一点很重要，因为从小的双极细胞(FISH)到现在的无髓延伸的大单极细胞，其初始部分被包裹在致密的被膜细胞内(图1)。Svaentiin(20)广泛报道了蛙脊神经节的细胞外电位，最近又讨论了细胞内电位(21)。Koketsu(12)研究了季铵离子对青蛙脊神经节细胞电位的影响，以及无钠溶液与体外培养的青蛙脊神经节细胞内电位的关系(13)。在蟾蜍中，伊藤对脊神经节细胞的细胞内潜能进行了广泛的观察(8，9，10)。除了Svaentiin(21)非常简短地提到了CAT细胞内drg电位之外，没有关于哺乳动物drg电位的类似工作。
DURING THE PAST DECADE the technique of recording intracellular potentials has been greatly extended, following the original work of Ling and Gerard (16) on recording from within single muscle cells. The dorsal root ganglion cell (hereafter drg cell) is of special interest because of its unusual anatomical and physiological properties. In addition, it is important because of phylogenetic emergence from small bipolar cells (fish) to the present large monopolar cell with nonmyelinated extension, an initial portion of which is enclosed within a dense covering of capsular cells (Fig. 1). Svaetichin (20) has reported extensively on the extracellular potentials of frog spinal ganglia and more recently discussed the intracellular poten-tials (21). Koketsu (12) studied the effect of quaternary ammonium ions on frog spinal ganglion cell potentials and also the relationship of Na-free solution to the intracellular potential of frog spinal ganglia in vitro (13). In the toad, Ito has made extensive observations on the intracellular potenti& of spinal ganglion cells (8, 9, 10). Except for a very brief mention of cat intracellular drg potentials by Svaetichin (21), there is no parallel work on mammalian drg, potentials.