Renal cortical tumors. Cytogenetic characterization.

Renal cortical tumors. Cytogenetic characterization.
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肾皮质肿瘤。

DOI:
10.1093/ajcp/92.4.408
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发表时间:
1989
影响因子:
3.5
通讯作者:
Sandberg,AA
Sandberg,AA
中科院分区:
医学4区
文献类型:
--
作者:
DalCin,P;Gaeta,J;Huben,R;Li,FP;ProutJr,GR;Sandberg,AA

文献摘要

被引文献

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作者检查了三个肾皮质肿瘤(腺瘤),发现了一致的染色体模式。这些肿瘤共有染色体异常(+.7,+7,+17,−Y)的组合。与此相反,他们都没有表现出染色体3p和5q的改变,在肾细胞癌中最常见的变化。这些患者的染色体异常可能定义为肾肿瘤的一个亚组,即所谓的腺瘤,在组织病理学检查中不能轻易与腺癌区分。
The authors examined three cortical tumors (adenomas) of the kidney and found a consistent chromosome pattern. A combination of chromosome abnormalities (+.7, +7, +17, −Y) was shared by these tumors. In contrast, none of them showed alterations of chromosome 3p and 5q, the most common changes in renal cell carcinomas. The chromosome abnormalities in these patients may define a subgroup of renal tumors, so-called adenomas, that cannot be distinguished easily from adenocarcinomas in histopathologic examination.