Diazepam in immediate post-myocardial infarct period. A double blind trial.
Diazepam in immediate post-myocardial infarct period. A double blind trial.
复制标题
地西泮用于心肌梗塞后即刻。
作者：
R. A. Dixon;R. Edwards;J. Pilcher
131例因心肌梗死入住冠心病监护室的男性患者，随后被证实，随机分配接受每6小时10 mg地西泮或匹配的安慰剂治疗48小时。在此期间，即使考虑到初始梗死严重程度的差异，也未发现治疗组之间致死性或非致死性快速性心律失常的发生率存在差异。除了嗜睡在地西泮治疗的患者中更常见外，两组患者的血压和心率数据以及患者自我评估的焦虑水平和症状具有可比性。
One hundred and thirty-one male patients admitted to a coronary care unit with myocardial infarction, later confirmed, were randomly allocated to receive either 10 mg diazepam every six hours, or a matched placebo, for 48 hours. During this period, no differences were found between the treatment groups in the incidence of fatal or non-fatal tachyarrhythmias even when account was taken of differences in the severity of the initial infarct. Monitored blood pressure and heart rate data were comparable as were the patients' self-assessed anxiety levels and symptoms, except that drowsiness was more common in the patients treated with diazepam.