Kinetics of individual limbs during level and slope walking with a unilateral transtibial bone-anchored prosthesis in the cat
Kinetics of individual limbs during level and slope walking with a unilateral transtibial bone-anchored prosthesis in the cat
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DOI：
10.1016/j.jbiomech.2018.05.021
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发表时间：
2018-07-25
影响因子：
2.4
通讯作者：
Prilutsky, Boris, I
中科院分区：
文献类型：
--
作者：
Jarrell, Joshua R.;Farrell, Brad J.;Prilutsky, Boris, I
正在进行的经皮骨锚定假体的动物临床前研究旨在改善肢体丧失患者的假体运动生物力学。将人类生物力学和假肢研究的成功发展转化为兽医学来治疗肢体缺失的动物要少得多。目前兽医学的护理标准是，如果远端节段无法挽救，则截肢整个肢体。骨锚定经皮假肢，开发的人与肢体损失，可能是有益的兽医实践。本研究的目的是检查猫在水平和斜坡行走时是否以及如何使用骨锚定被动经胫骨假体的肢体。在4只猫的右侧胫骨远端植入多孔钛植入物。在植入和假体连接之前和之后4-6个月，记录水平和坡度（+/- 50%）行走期间的地面反作用力和全身运动学。在所有猫和斜坡条件下，假肢的占空因数超过零（p < 0.05），范围为45.0- 60.6%。因此，猫使用假肢来移动，而不是用三条腿走路。与完整运动相比，假肢的地面反作用力、功率和功降低，而对侧后肢和前肢的地面反作用力、功率和功增加（p < 0.05）。这种不对称性可能是由于假肢产生的推进能量不足造成的，因为在动物中没有观察到疼痛或不适的迹象。我们的结论是，猫可以利用单侧骨锚定经胫骨假体四足水平和斜坡运动。(C)2018爱思唯尔有限公司版权所有。
Ongoing animal preclinical studies on transcutaneous bone-anchored prostheses have aimed to improve biomechanics of prosthetic locomotion in people with limb loss. It is much less common to translate successful developments in human biomechanics and prosthetic research to veterinary medicine to treat animals with limb loss. Current standard of care in veterinary medicine is amputation of the whole limb if a distal segment cannot be salvaged. Bone-anchored transcutaneous prostheses, developed for people with limb loss, could be beneficial for veterinary practice. The aim of this study was to examined if and how cats utilize the limb with a bone-anchored passive transtibial prosthesis during level and slope walking. Four cats were implanted with a porous titanium implant into the right distal tibia. Ground reaction forces and full-body kinematics were recorded during level and slope (+/- 50%) walking before and 4-6 months after implantation and prosthesis attachment. The duty factor of the prosthetic limb exceeded zero in all cats and slope conditions (p < 0.05) and was in the range of 45.0-60.6%. Thus, cats utilized the prosthetic leg for locomotion instead of walking on three legs. Ground reaction forces, power and work of the prosthetic limb were reduced compared to intact locomotion, whereas those of the contralateral hind- and forelimbs increased (p < 0.05). This asymmetry was likely caused by insufficient energy generation for propulsion by the prosthetic leg, as no signs of pain or discomfort were observed in the animals. We concluded that cats could utilize a unilateral bone-anchored transtibial prosthesis for quadrupedal level and slope locomotion. (C) 2018 Elsevier Ltd. All rights reserved.