ACUTE HEMORRHAGE FROM GASTRIC MALIGNANCY
ACUTE HEMORRHAGE FROM GASTRIC MALIGNANCY
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DOI：
10.1002/bjs.1800770106
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发表时间：
1990-01-01
影响因子：
9.6
通讯作者：
KEIGHLEY, MRB
中科院分区：
文献类型：
--
作者：
ALLUM, WH;BREARLEY, S;KEIGHLEY, MRB
对 30 例胃恶性肿瘤急性出血患者的表现、病理学和治疗进行了回顾。患者出血前的症状史通常少于 6 个月。腺癌是最常见的肿瘤类型，74% 为 IV 期病变。胃体病变的比例（57%）高于预期，表明这些是不同的胃肿瘤群体。 20 名患者接受了剖腹手术，其中 12 人接受了切除术。切除术的中位生存期为 17·0 个月。肿瘤无法切除或仅接受支持性治疗的患者中位生存期仅为2·5个月（P < 0·01）。腹膜或肝脏受累的证据应禁忌手术干预，因为这些患者术后死亡率很高。
The presentation, pathology and treatment of 30 patients with acute bleeding from gastric malignancies has been reviewed. Patients usually have a history of symptoms of less than 6 months prior to bleeding. Adenocarcinoma was the commonest type of tumour, and 74per cent were stage IV lesions. The proportion of lesions in the body of the stomach (57per cent) was greater than expected, suggesting that these are different populations of gastric tumour. Laparotomy was undertaken in 20 patients, 12 of whom had a resection. Resection was associated with a median survival of 17·0 months. Those with unresectable tumours or who were treated only by supportive measures had a median survival of only 2·5 months (P < 0·01). Evidence of peritoneal or liver involvement should contraindicate surgical intervention as these patients have a high postoperative mortality rate.