Blood glucose measurement by multiple attenuated total reflection and infrared absorption spectroscopy.
Blood glucose measurement by multiple attenuated total reflection and infrared absorption spectroscopy.
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通过多重衰减全反射和红外吸收光谱测量血糖。
DOI：
10.1109/10.55636
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发表时间：
1990
期刊：
影响因子：
--
通讯作者：
Lin,BC
中科院分区：
文献类型：
--
作者：
Mendelson,Y;Clermont,AC;Peura,RA;Lin,BC
通过常规红外吸收光谱法测量血液中葡萄糖的生理浓度的困难是由于水的固有高背景吸收。这种限制可以在很大程度上克服使用的CO/sub 2/激光器作为红外光源与多次衰减全反射（ATR）技术相结合。为了证明这种技术的适用性，在体外测量从实验红外激光光谱仪获得的血液中的葡萄糖进行了比较与独立的测量由标准YSI 23 A实验室葡萄糖分析仪。血糖浓度的连续测量能力在糖尿病患者的葡萄糖传感器的未来发展中是最重要的。<>
The difficulty of measuring physiological concentrations of glucose in blood by conventional infrared absorption spectroscopy is due to the intrinsic high background absorption of water. This limitation can be largely overcome by the use of a CO/sub 2/ laser as an infrared source in combination with a multiple attenuated total reflection (ATR) technique. To demonstrate the applicability of this technique, in vitro measurements of glucose in blood obtained from an experimental infrared laser spectrometer were compared with independent measurements made by a standard YSI 23A laboratory glucose analyzer. The capability of continuous measurement of blood glucose concentration is of primary importance in the future development of a glucose sensor for diabetic patients.<>