Involvement of the inferior frontal junction in cognitive control: Meta-analyses of switching and stroop studies
Involvement of the inferior frontal junction in cognitive control: Meta-analyses of switching and stroop studies
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DOI：
10.1002/hbm.20127
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发表时间：
2005-05-01
影响因子：
4.8
通讯作者：
von Cramon, DY
中科院分区：
文献类型：
--
作者：
Derrfuss, J;Brass, M;von Cramon, DY
越来越多的证据表明，后额外侧皮质的一个特定区域与认知控制过程密切相关。该区域位于额下沟和下中央前沟的交界处附近，被称为额下交界处（IFJ）。IFJ被证明是参与更新的任务表征，并被激活的任务切换范式，Stroop任务，和口头的n-回任务的主题内的调查。在这里，我们调查的参与IFJ在认知控制采用元分析方法。对功能性磁共振成像（fMRI）研究进行了两项定量荟萃分析。一项荟萃分析包括任务转换，设置转换和刺激反应（S-R）逆转研究的额叶激活，另一项包括颜色词Stroop研究的额叶激活。结果显示，在两种分析中，IFJ中的激活具有高度显著的聚集性。这些结果提供了强有力的证据，在开关和Stroop范式的IFJ的一贯参与。此外，他们支持我们的概念，区域专业化的额外侧皮质，这假定它不仅是middorsolateral部分，在认知控制中起着重要作用，但也IFJ。最后，我们的研究结果表明，如何定量荟萃分析可以用来测试的假设参与特定的大脑区域的认知控制。(c)2005 Wiley-Liss，Inc.
There is growing evidence that a specific region in the posterior frontolateral cortex is involved intimately in cognitive control processes. This region, located in the vicinity of the junction of the inferior frontal sulcus and the inferior precentral sulcus, was termed the inferior frontal junction (IFJ). The IFJ was shown to be involved in the updating of task representations and to be activated commonly in a within-subject investigation of a task-switching paradigm, the Stroop task, and a verbal n-back task. Here, we investigate the involvement of the IFJ in cognitive control by employing a meta-analytic approach. Two quantitative meta-analyses of functional magnetic resonance imaging (fMRI) studies were conducted. One meta-analysis included frontal activations from task-switching, set-shifting, and stimulus-response (S-R) reversal studies, the other included frontal activations from color word Stroop studies. Results showed highly significant clustering of activations in the IFJ in both analyses. These results provide strong evidence for the consistent involvement of the IFJ in both switching and Stroop paradigms. Furthermore, they support our concept of areal specialization in the frontolateral cortex, which posits that it is not only the middorsolateral part that plays an important role in cognitive control, but also the IFJ. Finally, our results demonstrate how quantitative meta-analyses can be used to test hypotheses about the involvement of specific brain regions in cognitive control. (c) 2005 Wiley-Liss, Inc.