The effect of paediatric syncope on health-related quality of life
The effect of paediatric syncope on health-related quality of life
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DOI：
10.1017/s1047951112000133
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发表时间：
2012-10-01
影响因子：
1
通讯作者：
Marino, Bradley S.
中科院分区：
文献类型：
--
作者：
Anderson, Jeffrey B.;Czosek, Richard J.;Marino, Bradley S.
背景：晕厥常见于儿童和青少年，最常见的是神经心源性晕厥。尚无关于晕厥对儿童健康相关生活质量影响的报道。研究方法：这是一项对2009年7月至2010年6月在辛辛那提儿童医院医学中心心脏研究所晕厥门诊就诊的患者进行的回顾性队列研究。使用PedsQL（TM）工具评估健康相关的生活质量。PedsQL（TM）评分与健康的历史对照和慢性疾病的历史对照进行了比较。结果：共纳入106例患者进行分析。总的来说，90%是白人，63%是女孩。中位年龄为15.1岁（8.2-21.6岁）。与健康对照组相比，患者的PedsQL（TM）评分较低：（75.2 vs 83.8，p < 0.0001）;身体健康总结（78.8 vs. 87.5，p < 0.0001）;心理社会健康总结（73.9对81.9，p < 0.001），情绪功能（68.9对79.3，p < 0.001）;和学校功能（66.4对81.1，p < 0.001）。社会功能无差异（86.2 vs 85.2，p=0.81）。患者的PedsQL（TM）总评分也低于糖尿病患者（p < 0.0001），与哮喘、终末期肾病、肥胖和结构性心脏病患者的评分相似。结论：晕厥儿童，虽然典型的良性病因，可以有低的健康相关的生活质量。
Background: Syncope is common in children and adolescents and most commonly represents neurocardiogenic syncope. No information has been reported regarding the effect of syncope on health-related quality of life in children. Methods: This was a retrospective cohort study of patients seen in the Heart Institute Syncope Clinic at Cincinnati Children's Hospital Medical Center between July, 2009 and June, 2010. Health-related quality of life was assessed using the PedsQL (TM) tool. PedsQL (TM) scores were compared with both healthy historical controls and historical controls with chronic illnesses. Results: A total of 106 patients were included for analysis. In all, 90% were Caucasian and 63% were girls. The median age was 15.1 years (8.2-21.6). Compared with healthy controls, patients had lower PedsQL (TM) scores: Total score (75.2 versus 83.8, p < 0.0001); Physical Health Summary (78.8 versus 87.5, p < 0.0001); Psychosocial Health Summary (73.9 versus 81.9, p < 0.001), Emotional Functioning (68.9 versus 79.3, p < 0.001); and School Functioning (66.4 versus 81.1, p < 0.001). No difference was seen in Social Functioning (86.2 versus 85.2, p=0.81). Patients also had lower PedsQL (TM) Total scores than patients with diabetes mellitus (p < 0.0001) and similar scores to patients with asthma, end-stage renal disease, obesity, and structural heart disease. Conclusion: Children with syncope, although typically benign in aetiology, can have low health-related quality of life.