PUBLIC ACCEPTANCE OF HUMAN GENE-THERAPY AND PERCEPTIONS OF HUMAN GENETIC MANIPULATION
PUBLIC ACCEPTANCE OF HUMAN GENE-THERAPY AND PERCEPTIONS OF HUMAN GENETIC MANIPULATION
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DOI：
10.1089/hum.1992.3.5-511
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发表时间：
1992-10-01
影响因子：
4.2
通讯作者：
MACER, DRJ
中科院分区：
文献类型：
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作者：
MACER, DRJ
基因治疗的临床试验正在不同的国家进行，预计不久将有更多的国家使用基因治疗。然而，公众对基因治疗的看法仍然知之甚少。1991年8月至10月，在日本进行了全国范围的邮件回复民意调查。共有54%的公众，65%的高中生物教师和54%的科学家表示他们愿意使用基因治疗，分别有66%，73%和62%的人表示他们愿意对他们的孩子使用基因治疗。在日本，基因治疗的接受度似乎越来越高，尽管大约有四分之一的人反对它，但人类基因操作的可接受性和感知的利益和风险背后的基本推理被提出，这些被发现与1990年5月在新西兰进行的一项类似调查中表达的推理大致相似。公众的看法也与欧洲和美国的看法进行了比较。人们从基因操纵中既看到了好处，也看到了风险。在新西兰的高中生物课上，与遗传工程相关的伦理、社会和环境问题的教学似乎比日本多。在日本和新西兰，约90%的公众支持在课程中加入与科学和技术有关的社会问题的讨论。
Clinical trials of gene therapy are underway in different countries, and further countries can be expected to use gene therapy soon. Little remains known, however, about public perceptions of gene therapy. Nationwide mail response opinion surveys were conducted in Japan in August-October, 1991. A total of 54% of the public, 65% of the high school biology teachers, and 54% of the scientists who responded said that they would be willing to use gene therapy, and 66%, 73%, and 62%, respectively, said that they would be willing to use gene therapy on their children. There appears to be growing acceptance of gene therapy in Japan, although about one-quarter of the population are against it. The underlying reasoning behind the acceptability of human genetic manipulation and perceived benefits and risks are presented, and these were found to be generally similar to reasoning expressed in a similar survey conducted in New Zealand in May, 1990. Public perceptions are also compared to those in Europe and the United States. People perceive both benefits and risks from genetic manipulation. There appears to be more teaching of ethical, social, and environmental issues associated with genetic engineering in senior high school biology classes in New Zealand than in Japan. In Japan and New Zealand, about 90% of the public would support including discussion of social issues associated with science and technology in the curriculum.