ALFRED: an allele frequency database for diverse populations and DNA polymorphisms
ALFRED: an allele frequency database for diverse populations and DNA polymorphisms
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DOI：
10.1093/nar/28.1.361
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发表时间：
2000-01-01
影响因子：
14.9
通讯作者：
Kidd, KK
中科院分区：
文献类型：
--
作者：
Cheung, KH;Osier, MV;Kidd, KK
我们开发了一个可公开访问的数据库（ALFRED，ALLele FREquency 数据库），该数据库对各种人群样本和 DNA 多态性的等位基因频率数据进行编目，该数据库可通过我们的实验室（Kidd：Lab）网站访问：http://info.med.yale.edu/ Genetics/kkidd 。 ALFRED 目前包含 60 个群体和 156 个遗传系统的数据，包括单核苷酸多态性 (SNP)、短串联重复多态性 (STRP)、可变串联重复次数 (VNTR) 和插入删除多态性。虽然无法提供所有人群 DNA 多态性组合的数据，但已输入 2000 多个等位基因频率表，我们的数据库旨在 (i) 满足我们的特定研究要求以及更广泛的科学目标； (ii) 允许研究人员和感兴趣的教育工作者轻松导航和检索他们感兴趣的数据； (iii) 整合其他相关公共数据库的链接，例如 dbSNP、GenBank 和 PubMed。
We have developed a publicly accessible database (ALFRED, the ALlele FREquency Database) that catalogues allele frequency data for a wide range of population samples and DNA polymorphisms, This database is web-accessible through our laboratory (Kidd: Lab) Web site: http://info.med.yale.edu/genetics/kkidd . ALFRED currently contains data on 60 populations and 156 genetic systems including single nucleotide polymorphisms (SNPs), short tandem repeat polymorphisms (STRPs), variable number of tandem repeats (VNTRs) and insertion-deletion polymorphisms. While data are not available for all population-DNA polymorphism combinations, over 2000 allele frequency tables have been entered, Our database is designed (i) to address our specific research requirements as well as broader scientific objectives; (ii) to allow researchers and interested educators to easily navigate and retrieve data of interest to them; and (iii) to integrate links to other related public databases such as dbSNP, GenBank and PubMed.