Use of palivizumab and infection control measures to control an outbreak of respiratory syncytial virus in a neonatal intensive care unit confirmed by real-time polymerase chain reaction
Use of palivizumab and infection control measures to control an outbreak of respiratory syncytial virus in a neonatal intensive care unit confirmed by real-time polymerase chain reaction
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DOI：
10.1016/j.jhin.2010.12.012
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发表时间：
2011-04-01
影响因子：
6.9
通讯作者：
Cormican, M.
中科院分区：
文献类型：
--
作者：
O'Connell, K.;Boo, T. W.;Cormican, M.
呼吸道合胞病毒(RSV)是一种潜在威胁早产儿生命的感染。我们报告2010年2月发生在我们医院新生儿重症监护病房(NICU)的一次涉及四名婴儿的暴发。实时荧光定量聚合酶链式反应证实呼吸道合胞病毒A感染。NICU中的所有婴儿都接受了帕利维珠单抗治疗。没有其他有症状的病例，反复呼吸道合胞病毒监测证实，在该单位内没有进一步的交叉传播。这次暴发突显了病房床位占用率极高的感染控制挑战，以及分子方法在促进检测和管理方面的作用。(C)2011年医疗感染学会。爱思唯尔有限公司出版。保留所有权利。
Respiratory syncytial virus (RSV) is a potentially life-threatening infection in premature infants. We report an outbreak involving four infants in the neonatal intensive care unit (NICU) of our hospital that occurred in February 2010. RSV A infection was confirmed by real-time polymerase chain reaction. Palivizumab was administered to all infants in the NICU. There were no additional symptomatic cases and repeat RSV surveillance confirmed that there was no further cross-transmission within the unit. The outbreak highlighted the infection control challenge of very high bed occupancy in the unit and the usefulness of molecular methods in facilitating detection and management. (C) 2011 the Healthcare Infection Society. Published by Elsevier Ltd. All rights reserved.