The recent prevalence of osteoporosis and low bone mass in the United States based on bone mineral density at the femoral neck or lumbar spine.
The recent prevalence of osteoporosis and low bone mass in the United States based on bone mineral density at the femoral neck or lumbar spine.
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DOI：
10.1002/jbmr.2269
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发表时间：
2014-11
期刊：
影响因子：
--
通讯作者：
Dawson-Hughes B
中科院分区：
文献类型：
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作者：
Wright NC;Looker AC;Saag KG;Curtis JR;Delzell ES;Randall S;Dawson-Hughes B
本研究的目的是根据美国50岁及以上成年人股骨颈和腰椎的骨矿物质密度（BMD）估计骨质疏松症和低骨量的患病率。我们应用了来自2005-2010年全国健康与营养检查调查和2010年美国人口普查的50岁及以上非机构人口的骨质疏松症或股骨颈或腰椎低骨量的患病率估计（根据年龄、性别和种族/民族调整到2010年人口普查），以确定患有骨质疏松症和低骨量的美国老年居民的总数。2010年，美国50岁及以上的成年人超过9900万人。根据骨质疏松症10.3%的总体患病率，我们估计2010年有1020万老年人患有骨质疏松症。总体骨量低患病率为43.9%，据此我们估计有4340万老年人骨量低。我们估计有770万非西班牙裔白人、50万非西班牙裔黑人和60万墨西哥裔美国成年人患有骨质疏松症，另有3380万人、290万人和200万人骨量低。2010年，骨质疏松症和股骨颈或腰椎骨量过低联合影响了约5360万美国老年人。虽然大多数患有骨质疏松症或低骨量的个体是非西班牙裔白人女性，但其他种族/民族群体的大量男性和女性也患有骨质疏松症或低骨量。
The goal of our study was to estimate the prevalence of osteoporosis and low bone mass based on bone mineral density (BMD) at the femoral neck and the lumbar spine in adults 50 years and older in the United States (US). We applied prevalence estimates of osteoporosis or low bone mass at the femoral neck or lumbar spine (adjusted by age, sex, and race/ethnicity to the 2010 Census) for the non-institutionalized population age 50 years and older from the National Health and Nutrition Examination Survey 2005–2010 to 2010 US Census population counts to determine the total number of older US residents with osteoporosis and low bone mass. There were over 99 million adults 50 years and older in the US in 2010. Based on an overall 10.3% prevalence of osteoporosis, we estimated that in 2010 10.2 million older adults had osteoporosis. The overall low bone mass prevalence was 43.9%, from which we estimated that 43.4 million older adults had low bone mass. We estimated that 7.7 million non-Hispanic White, 0.5 million non-Hispanic Black, and 0.6 million Mexican American adults had osteoporosis and another 33.8, 2.9, and 2.0 million had low bone mass, respectively. When combined, osteoporosis and low bone mass at the femoral neck or lumbar spine affected an estimated 53.6 million older US adults in 2010. Although most of the individuals with osteoporosis or low bone mass were non-Hispanic White women, a substantial number of men and women from other racial/ethnic groups also had osteoporotic BMD or low bone mass.