Environment-sensitive behavior of fluorescent molecular rotors.
Environment-sensitive behavior of fluorescent molecular rotors.
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DOI：
10.1186/1754-1611-4-11
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发表时间：
2010-09-15
影响因子：
5.6
通讯作者：
Theodorakis EA
中科院分区：
文献类型：
--
作者：
Haidekker MA;Theodorakis EA
分子转子是一组荧光分子，在光激发下形成扭曲的分子内电荷转移（TICT）状态。当发生分子内扭曲时，分子转子通过发射红移的发射带或通过非辐射弛豫返回到基态。的发射性能是强烈的溶剂依赖性，和溶剂粘度是从平面（非扭曲）构象的荧光量子产率的主要决定因素。这种粘度敏感的行为引起了在例如流体力学、聚合物化学、细胞生理学和食品科学中的应用。然而，体积粘度和分子转子与其环境的分子尺度相互作用之间的关系还没有完全理解。本文综述了分子水平上转子-溶剂相互作用的相关理论，以及这种相互作用是如何导致粘度敏感行为的。此外，分子转子作为微粘度传感器的当前应用进行了综述，并提出了如何提高测量精度和精度的工程方面。
Molecular rotors are a group of fluorescent molecules that form twisted intramolecular charge transfer (TICT) states upon photoexcitation. When intramolecular twisting occurs, the molecular rotor returns to the ground state either by emission of a red-shifted emission band or by nonradiative relaxation. The emission properties are strongly solvent-dependent, and the solvent viscosity is the primary determinant of the fluorescent quantum yield from the planar (non-twisted) conformation. This viscosity-sensitive behavior gives rise to applications in, for example, fluid mechanics, polymer chemistry, cell physiology, and the food sciences. However, the relationship between bulk viscosity and the molecular-scale interaction of a molecular rotor with its environment are not fully understood. This review presents the pertinent theories of the rotor-solvent interaction on the molecular level and how this interaction leads to the viscosity-sensitive behavior. Furthermore, current applications of molecular rotors as microviscosity sensors are reviewed, and engineering aspects are presented on how measurement accuracy and precision can be improved.