Salivary immunoglobulins in patients with juvenile periodontitis and their healthy siblings.
Salivary immunoglobulins in patients with juvenile periodontitis and their healthy siblings.
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幼年牙周炎患者及其健康兄弟姐妹的唾液免疫球蛋白。
DOI：
10.1902/jop.1984.55.1.9
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发表时间：
1984
影响因子：
4.3
通讯作者：
E. Grönblad
中科院分区：
文献类型：
--
作者：
L. Sandholm;E. Grönblad
采用固相放射免疫法测定了21例青少年牙周炎（JP）患者、27例健康同胞和17例年龄匹配的健康对照者未受刺激的唾液免疫球蛋白IgA、IgG和IgM的浓度。JP组的IgA浓度增加，平均为188 +/- 32.5 (SE) mg/L，而健康兄弟姐妹的平均值为139 +/- 21.2 mg/L，对照组的平均值为130 +/- 24.5 mg/L。JP患者IgG水平升高45.6 +/- 12.5 mg/L，而兄弟姐妹为18.1 +/- 5.9 mg/L，对照组为21.0 +/- 5.6 mg/L。JP组的平均IgM为22.5 +/- 5.4 mg/L，兄弟姐妹为13.3 +/- 2.9 mg/L，对照组为8.7 +/- 1.6 mg/L，表明JP组和兄弟姐妹的IgM均有所增加。与对照组相比，青少年牙周炎组的平均IgM值有显著差异。P < 0.01)。
The concentrations of the salivary immunoglobulins IgA, IgG and IgM were determined with a solid phase radioimmunoassay in the unstimulated whole saliva of 21 patients with juvenile periodontitis (JP), their 27 healthy siblings and 17 healthy age-matched controls. In the JP group the concentrations of IgA were increased, averaging 188 +/- 32.5 (SE) mg/L as compared with the mean of 139 +/- 21.2 mg/L in their healthy siblings and 130 +/- 24.5 mg/L in the controls. An elevation was found in the amount of IgG in the JP patients 45.6 +/- 12.5 mg/L as compared with 18.1 +/- 5.9 mg/L in the siblings and 21.0 +/- 5.6 mg/L in the controls. The mean IgM was 22.5 +/- 5.4 mg/L in the JP group, 13.3 +/- 2.9 mg/L in the siblings and 8.7 +/- 1.6 mg/L in the controls, indicating an increase of IgM in the JP group and the siblings. A significant difference was found in the mean IgM values in the juvenile periodontitis group when compared to the control group. (0.02 greater than P greater than 0.01).