Comparative MR imaging study of brain maturation in kittens with T1, T2, and the trace of the diffusion tensor
Comparative MR imaging study of brain maturation in kittens with T1, T2, and the trace of the diffusion tensor
复制标题
DOI：
10.1148/radiology.210.1.r99ja09133
复制
发表时间：
1999-01-01
期刊：
影响因子：
19.7
通讯作者：
Pierpaoli, C
中科院分区：
文献类型：
--
作者：
Baratti, C;Barnett, AS;Pierpaoli, C
目的：评估产后大脑发育中的松弛时间和定向平均水扩散系数 D-oav 的时程。材料和方法：在四只小猫的 8 个时间点获得 T1、T2 的多部分图和扩散张量迹线 (Trace[D] = 3 x D-oav)。结果：在成年猫中，白色和白色猫的 D-oav 约为 700 mu m(2)/sec。灰质。在新生儿中，白质中的D-oav为1,100-1,350μm(2)/秒，灰质中的D-oav为1,000μm(2)/秒。对于所有解剖区域和时间点，D-oav 和 1/T2 之间的相关性很高（R-2 = 0.87，P
PURPOSE: To assess the time-course of the relaxation times and the orientationally averaged water diffusion coefficient D-oav in postnatal brain development.MATERIALS AND METHODS: Multisection maps of T1, T2, and the trace of the diffusion tensor (Trace[D] = 3 x D-oav) were obtained in four kittens at eight time points.RESULTS: In the adult, D-oav was about 700 mu m(2)/sec in both white and gray matter. In the newborn, D-oav was 1,100-1,350 mu m(2)/sec in white matter and 1,000 mu m(2)/sec in gray matter. For ail anatomic regions and time points, the correlation between D-oav and 1/T2 was high (R-2 = 0.87, P