The Occurrence or Fibrillary Glomerulonephritis in Patients with Diabetes Mellitus May Not Be Coincidental: A Report of Four Cases
The Occurrence or Fibrillary Glomerulonephritis in Patients with Diabetes Mellitus May Not Be Coincidental: A Report of Four Cases
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DOI：
10.1155/2013/935172
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发表时间：
2013-01-01
影响因子：
0.8
通讯作者：
Rodriguez-Perez, Jose C.
中科院分区：
文献类型：
--
作者：
Gonzalez-Cabrera, Fayna;Henriquez-Palop, Fernando;Rodriguez-Perez, Jose C.
虽然原纤维性肾小球肾炎的临床表现与大多数类型的肾小球肾炎相似，但通常难以诊断。临床表现包括蛋白尿、镜下血尿、肾病综合征和肾功能损害。纤维性肾小球肾炎的诊断只能通过肾活检来证实，并且必须包括电子显微镜下证实的超微结构结果。我们报告了4例年龄在45-50岁之间的2型糖尿病（T2DM）合并动脉高血压的病例。所有患者肾活检均发现有原纤维。在糖尿病的背景下纤维的鉴别诊断也进行了讨论。
Although clinical presentation of fibrillary glomerulonephritis is similar to most forms of glomerulonephritis, it is usually difficult to make the diagnosis. Clinical manifestations include proteinuria, microscopic haematuria, nephrotic syndrome, and impairment of renal function. A diagnosis of fibrillary glomerulonephritis is only confirmed by renal biopsy and it must comprise electronmicroscopy-verified ultrastructural findings. We report four cases between 45-50 years old with documented type 2 diabetes mellitus (T2DM) and arterial hypertension. All patients were found to have fibrils on kidney biopsy. The differential diagnosis of fibrils in the setting of diabetes mellitus is also discussed.