(EtO)3SiH-Promoted Palladium-Catalyzed Isomerization of Olefins: Convenient Synthesis of Internal Alkenes from Terminal Alkenes
(EtO)3SiH-Promoted Palladium-Catalyzed Isomerization of Olefins: Convenient Synthesis of Internal Alkenes from Terminal Alkenes
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DOI：
10.1055/s-0033-1340290
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发表时间：
2014-02-13
期刊：
影响因子：
2
通讯作者：
Xu, Li-Wen
中科院分区：
文献类型：
--
作者：
Bai, Xing-Feng;Song, Tao;Xu, Li-Wen
研究了PdCl_2（PPh_3）（2）和含氢硅烷[（EtO）（3）SiH]原位生成的钯催化剂体系对4，4-联芳基取代1-丁烯的一碳迁移和异构化反应的催化活性，其中（EtO）（3）SiH在钯催化的末端烯烃的一碳迁移和异构化反应中起关键作用.该催化方法用于合成木薯素C的关键结构单元，具有较高的产率和选择性。
The catalytic activity of an in situ forming palladium catalyst system generated from PdCl2(PPh3)(2) and hydrosilane [(EtO)(3)SiH] was revealed in the one-carbon migration and isomerization of 4,4-biaryl-substituted 1-butenes, in which the (EtO)(3)SiH plays a key role in the palladium-catalyzed one-carbon migration and subsequent isomerization of terminal alkenes. This catalytic protocol is applied in the synthesis of a key building block of cassumunin C in high yield and promising selectivity.