Short interspersed repeats in rabbit DNA can provide functional polyadenylation signals.
Short interspersed repeats in rabbit DNA can provide functional polyadenylation signals.
复制标题
兔 DNA 中的短散布重复序列可以提供功能性聚腺苷酸化信号。
DOI：
10.1093/oxfordjournals.molbev.a040583
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发表时间：
1990
影响因子：
10.7
通讯作者：
Hardison,RC
中科院分区：
文献类型：
--
作者：
Krane,DE;Hardison,RC
对兔子DNA中37个被称为C重复序列的短重复元件（西内斯）的分析显示，其中三个为它们插入的基因提供功能性聚腺苷酸化信号。类似的作用已被归因于特定的个别西内斯在啮齿动物和灵长类动物之前，这表明这些作用可能是共同的西内斯在所有哺乳动物的订单。虽然大多数西内斯似乎对基因组个体的影响很小，但观察到36个兔C重复序列中有3个提供功能序列，这表明哺乳动物基因组中西内斯的维持机制。
Analysis of 37 short repetitive elements (SINEs) in rabbit DNA that are known as C repeats has revealed three that contribute functional polyadenylation signals to genes into which they have been inserted. Similar roles have been attributed to particular individual SINEs in rodents and primates before, suggesting that these roles may be common to SINEs in all mammalian orders. Although most SINEs appear to have little influence on the genome individually, the observation that three of 36 rabbit C repeats provide functional sequences suggests a mechanism for the maintenance of SINEs within mammalian genomes.