Method optimization for determination of selected perfluorinated alkylated substances in water samples
Method optimization for determination of selected perfluorinated alkylated substances in water samples
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DOI：
10.1007/s00216-006-0902-7
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发表时间：
2006-12-01
影响因子：
4.3
通讯作者：
Gans, Oliver
中科院分区：
文献类型：
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作者：
Gonzalez-Barreiro, Carmen;Martinez-Carballo, Elena;Gans, Oliver
近年来，全氟烷基化物质（PFAS）作为一类新的全球性污染物出现。除了作为工业上重要的化合物组之外，PFAS被认为是高毒性和非常持久的化学品，其在全世界范围内普遍污染人类血液和野生动物。因此，它们被视为PBT（持久性、生物累积性和毒性）化学品。两个全面的方法已被开发用于测定11个最环保的PFAS（七个全氟烷基羧酸盐，两个全氟烷基磺酸盐，和两个全氟辛烷磺酰胺）在水溶液样品。采用液-液萃取（LLE）和固相萃取（SPE）方法对样品进行分离，采用液相色谱-电喷雾-串联质谱（LC-ESI-MS-MS）对目标化合物进行定性和定量。对于900 mL水样的富集，LLE检测限为0.26 - 0.62 ng L-1;碳链长于C-7的PFAS的回收率极佳（80-93%）。利用固相萃取，在酸性条件下可以有效地提取碳链< C-10的羧酸盐（70-98%），在碱性条件下可以有效地提取全氟辛烷磺酸和全氟辛基磺酰胺（分别为81%和96%），最大允许浓度为0.25 - 0.64纳克/升。液液平衡法成功地应用于奥地利废水样品。
In recent years perfluorinated alkylated substances (PFAS) have appeared as a new class of global pollutant. Besides being an industrially important group of compounds, PFAS are regarded as highly toxic and extraordinarily persistent chemicals that pervasively contaminate human blood and wildlife throughout the world. They are therefore regarded as PBT (persistent, bioaccumulative, and toxic) chemicals. Two comprehensive methods have been developed for determination of eleven of the most environmentally relevant PFAS (seven perfluoroalkylcarboxylates, two perfluoroalkylsulfonates, and two perfluoroctanesulfonamides) in aqueous samples. The compounds were isolated by liquid-liquid extraction (LLE) and solid-phase extraction (SPE), and identification and quantification of the target analytes were achieved by liquid chromatography-electrospray ionization-tandem mass spectrometry (LC-ESI-MS-MS). With LLE detection limits ranged from 0.26 to 0.62 ng L-1 for enrichment of 900-mL water samples; recovery of PFAS with a carbon chain longer than C-7 was excellent (80-93%). With SPE, carboxylates with carbon chains < C-10 could be extracted efficiently (70-98%) under acidic conditions, and PFOS and PFOSA could be extracted efficiently (81% and 96%, respectively) under basic conditions, resulting in MDLs between 0.25 and 0.64 ng L-1. The LLE method was applied successfully to Austrian wastewater effluent samples.