Methylphenidate effects in learning disabilities. Psychometric changes.
Methylphenidate effects in learning disabilities. Psychometric changes.
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哌甲酯对学习障碍的影响。
DOI：
10.1001/archpsyc.1976.01770060003001
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发表时间：
1976
影响因子：
--
通讯作者：
D. Klein
中科院分区：
文献类型：
--
作者：
R. Gittelman;D. Klein
61 名智力中等、学习明显滞后但没有行为障碍的儿童接受了为期 12 周的安慰剂或盐酸哌甲酯治疗。哌醋甲酯有助于提高许多心理测试的表现，但不影响标准化成绩测试的表现。所调查的患者特征均不能严格预测药物效果。哌醋甲酯似乎对视觉运动过程有特定的影响，这反过来又对表现任务产生积极影响，但对语言任务没有影响。在本研究的条件下，尽管数据提供了对儿童认知功能的刺激作用的证据，但单独使用哌醋甲酯治疗并不能成为改善阅读能力的有效药物。
Sixty-one children of average intelligence with appreciable learning lags, but no behaviour disorders, received placedo or methylphenidate hydrochloride for a 12-week period. Methylphenidate was instrumental in improving performance on many psychological tests, but did not affect performance on standardized achievement tests. None of the patient characteristics investigated was stringly predictive of drug effect. Methylphenidate seems to have a specific effect on visualmotor processes, which in turn positively affect performance tasks, but not verbal tasks. Under the conditions of this study, methylphenidate treatment alone did not emerge as a useful agent for the amelioration of reading performance, although the data provide evidence for stimulation effects on children's cognitive functions.