CT Attenuation of Periaortic Adipose Tissue in Abdominal Aortic Aneurysms.
CT Attenuation of Periaortic Adipose Tissue in Abdominal Aortic Aneurysms.
复制标题
腹主动脉瘤主动脉周围脂肪组织的 CT 衰减。
DOI：
10.1148/ryct.230250
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发表时间：
2024
期刊：
影响因子：
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通讯作者：
Williams,MichelleC
中科院分区：
文献类型：
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作者：
Debono,Samuel;Tzolos,Evangelos;Syed,MaazBJ;Nash,Jennifer;Fletcher,AlexanderJ;Dweck,MarcR;Newby,DavidE;Dey,Damini;Forsythe,RachaelO;Williams,MichelleC
目的：评估主动脉周围脂肪组织在CT血管造影中的衰减， 不同的腹主动脉瘤疾病状态。材料和方法在2018年1月至2019年12月的回顾性观察研究中， 2022，在CT上评估主动脉周围脂肪组织衰减 无症状或有症状（包括 破裂）腹主动脉瘤和对照无动脉瘤。 使用半自动软件测量脂肪组织衰减， 腹主动脉的动脉瘤和非动脉瘤段 以及皮下和内脏脂肪组织。主动脉周围脂肪 三组之间的组织衰减值用 Studentt检验和Wilcoxon秩和检验， 结果88例受试者（中位年龄70岁[IQR，65-78]; 78 男性和10名女性患者）包括：70名腹部手术患者 主动脉瘤（40例无症状和30例有症状，包括24例 破裂）和18个对照。没有证据表明， 腹主动脉瘤段主动脉周围脂肪组织衰减 无症状患者与对照组（−81.44 HU ± 7 [SD]） vs −83.27 HU ± 9;P= .43）， 无症状患者之间的非囊性节段衰减 与对照组相比（−75.43 HU ± 8 vs −78.81 HU ± 6;P= .08）。然而，有症状的患者 在两组中显示了更高的主动脉周围脂肪组织衰减 不对称（−57.85 HU ± 7;P< 0.0001）和非囊性节段（−58.16 HU ± 8;P<0.0001） 结论主动脉周围脂肪组织的CT衰减在稳定期不增加， 腹主动脉瘤病有一个普遍的增加， 有症状疾病患者的衰减，可能反映了 急性破裂的全身后果。关键词：腹主动脉瘤，主动脉周围脂肪 组织衰减，CT AngiographyClinicalTrials.gov注册号NCT 02229006 © RSNA，2024
PurposeTo assess periaortic adipose tissue attenuation at CT angiography in different abdominal aortic aneurysm disease states.Materials and MethodsIn a retrospective observational study from January 2018 to December 2022, periaortic adipose tissue attenuation was assessed at CT angiography in patients with asymptomatic or symptomatic (including rupture) abdominal aortic aneurysms and controls without aneurysms. Adipose tissue attenuation was measured using semiautomated software in periaortic aneurysmal and nonaneurysmal segments of the abdominal aorta and in subcutaneous and visceral adipose tissue. Periaortic adipose tissue attenuation values between the three groups were assessed using Studentttests and Wilcoxon rank sum tests followed by a multiregression model.ResultsEighty-eight individuals (median age, 70 years [IQR, 65–78]; 78 male and 10 female patients) were included: 70 patients with abdominal aortic aneurysms (40 asymptomatic and 30 symptomatic, including 24 with rupture) and 18 controls. There was no evidence of differences in the periaortic adipose tissue attenuation in the aneurysmal segment in asymptomatic patients versus controls (−81.44 HU ± 7 [SD] vs −83.27 HU ± 9;P= .43) and attenuation in nonaneurysmal segments between asymptomatic patients versus controls (−75.43 HU ± 8 vs −78.81 HU ± 6;P= .08). However, symptomatic patients demonstrated higher periaortic adipose tissue attenuation in both aneurysmal (−57.85 HU ± 7;P< .0001) and nonaneurysmal segments (−58.16 HU ± 8;P< .0001) when compared with the other two groups.ConclusionPeriaortic adipose tissue CT attenuation was not increased in stable abdominal aortic aneurysm disease. There was a generalized increase in attenuation in patients with symptomatic disease, likely reflecting the systemic consequences of acute rupture.Keywords:Abdominal Aortic Aneurysm, Periaortic Adipose Tissue Attenuation, CT AngiographyClinicalTrials.gov registration no. NCT02229006© RSNA, 2024