Usefulness of combined intravascular ultrasound parameters to predict functional significance of coronary artery stenosis and determinants of mismatch
Usefulness of combined intravascular ultrasound parameters to predict functional significance of coronary artery stenosis and determinants of mismatch
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DOI：
10.4244/eijv11i2a30
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发表时间：
2015-06-01
期刊：
影响因子：
6.2
通讯作者：
Kim, Kwon-Bae
中科院分区：
文献类型：
--
作者：
Cho, Yun-Kyeong;Nam, Chang-Wook;Kim, Kwon-Bae
目的：联合血管内超声（IVUS）参数在功能显著性预测中的有效性以及IVUS和血流储备分数（FFR）之间的差异尚未得到很好的定义。因此，本研究旨在：1）评价组合IVUS参数（即最小管腔面积（MLA）和斑块负荷百分比（%PB））在冠状动脉狭窄的功能显著性预测中的诊断准确性;以及2）定义影响FFR值与IVUS参数之间关系的因素。方法和结果：在11个国际中心，对945处重大心外膜冠状动脉病变（886例患者）同时进行了IVUS和FFR测量。功能显著性定义为FFR
Aims: Efficacy of combined intravascular ultrasound (IVUS) parameters in functional significance prediction and discrepancy between IVUS and fractional flow reserve (FFR) have not been well defined. This study therefore aimed to: 1) evaluate the diagnostic accuracy of combined IVUS parameters, namely minimal lumen area (MLA) and percent plaque burden (%PB), in functional significance prediction of coronary artery stenosis; and 2) define factors that affect the relation between FFR value and IVUS parameters.Methods and results: At 11 international centres, IVUS and FFR measurements were concurrently performed in 945 major epicardial coronary artery lesions (886 patients). Functional significance was defined as FFR