Moderate alcohol consumption in older adults is associated with better cognition and well-being than abstinence
Moderate alcohol consumption in older adults is associated with better cognition and well-being than abstinence
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DOI：
10.1093/ageing/afm001
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发表时间：
2007-05-01
期刊：
影响因子：
6.7
通讯作者：
Melzer, David
中科院分区：
文献类型：
--
作者：
Lang, Iain;Wallace, Robert B.;Melzer, David
背景资料：有证据表明，饮酒与老年人的身体健康状况之间存在U型关系，因此适度饮酒比戒酒或酗酒更能改善老年人的身体健康状况，但与不饮酒相比，适度饮酒是否能改善老年人的认知和心理健康状况尚未得到研究。目的：评估饮酒与中老年人认知健康之间的关系。设计：前瞻性观察研究。环境/参与者：6005名50岁及以上的人参加了英国老龄化纵向研究（艾尔莎）的第一波，他们不是问题饮酒者。我们检查了认知功能、主观幸福感和抑郁症状，并比较了从未饮酒、戒酒和每天饮酒<1.2杯的风险< 2 and >。对于男性和女性来说，更好的认知和主观幸福感，以及更少的抑郁症状，与从不喝酒的人相比，与适度饮酒有关。在中年和老年男性和女性中，适度饮酒与更好的认知健康有关，而不是戒酒。
Background: there is evidence of a U-shaped association between alcohol consumption and physical health outcomes in older people, such that moderate drinking is associated with better outcomes than abstinence or heavy drinking, but whether moderate drinking in older people is associated with better cognition and mental health than non-drinking has not been explored.Objective: to assess the relationship between drinking and cognitive health in middle-aged and older people.Design: prospective observational study.Setting/Participants: six thousand and five individuals aged 50 and over who participated in Wave 1 of the English Longitudinal Study of Ageing (ELSA) and who were not problem drinkers.Exposure and outcome variables: we examined cognitive function, subjective well-being, and depressive symptoms, and compared the risks associated with having never drunk alcohol, having quit drinking, and drinking at < 1, < 2 and > 2 drinks per day.Results: for both men and women, better cognition and subjective well-being, and fewer depressive symptoms, were associated with moderate levels of alcohol consumption than with never having drunk any.Conclusions: in middle-aged and older men and women, moderate levels of alcohol consumption are associated with better cognitive health than abstinence.