Role of dopamine in malignant tumor growth

Role of dopamine in malignant tumor growth
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DOI:
10.1385/endo:12:3:237
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发表时间:
2000-06-01
期刊:
影响因子:
3.7
通讯作者:
Dasgupta, PS
Dasgupta, PS
中科院分区:
医学3区
文献类型:
--
作者:
Basu, S;Dasgupta, PS

文献摘要

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多巴胺是一种单胺神经递质和/或神经激素,在控制几种垂体前叶激素的分泌、心血管和肾功能中的调节作用已经被临床医生广泛用于治疗目的。除了多巴胺的这些重要功能外,最近的一些报道还表明它在调节恶性细胞增殖和控制荷瘤动物的免疫功能中的新作用,因此,在这篇文章中,我们讨论了所有相关的信息多巴胺和恶性肿瘤的生长,以了解在神经递质和/或神经激素的水平上的宿主-肿瘤的关系。
The regulatory role of dopamine, a monoamine neurotransmitter and/or a neurohormone in controlling the secretion of several anterior pituitary hormones, cardiovascular, and renal functions, has already been extensively used by clinicians for therapeutic purposes, In addition to these important functions of dopamine, some recent reports also indicate its novel role in regulating malignant cell proliferation and controlling immune functions in tu mor-bearing animals, Therefore, in this article, we discuss all the relevant information correlating dopamine and malignant tumor growth in order to understand the host-tumor relationship at the level of a neurotransmitter and/or a neurohormone.