Evidence for a deficit in the salience attribution to errors in smokers
Evidence for a deficit in the salience attribution to errors in smokers
复制标题
DOI：
10.1016/j.drugalcdep.2009.08.014
复制
发表时间：
2010-01-15
影响因子：
4.2
通讯作者：
Kuijpers, Ilse
中科院分区：
文献类型：
--
作者：
Franken, Ingmar H. A.;van Strien, Jan W.;Kuijpers, Ilse
尽管会产生不良后果，但持续使用物质是吸烟等成瘾行为的标志之一。在本研究中，我们使用事件相关电位（ERP）调查的一个方面的不良后果：吸烟者与非吸烟者的错误反应。本研究的目的是确定吸烟者是否显示错误处理缺陷，使用错误相关负性（ERN）和错误正性（Pe）测量。ERPs在埃里克森侧翼任务记录吸烟者和非吸烟对照组。吸烟者在犯错误后表现出与对照组相同的ERN反应。然而，与对照组相比，后期Pe反应降低。在行为水平上，我们观察到吸烟者在不一致试验中错误率增加的趋势。目前的研究结果表明，吸烟与减少错误处理。更具体地说，虽然最初的错误处理似乎完好无损，但反映表现错误的动机意义的大脑系统似乎受到了损害。有人认为，这些认知缺陷可能导致或有助于吸烟行为和成瘾行为的持续存在。(c)2009爱思唯尔爱尔兰有限公司版权所有
The persisting use of substances despite of adverse consequences is one of the hallmarks of addictive behaviors such as cigarette smoking. In the present study we used event-related potentials (ERPs) to investigate one aspect of adverse consequences: responses to errors in smokers versus non-smokers. The aim of this study was to determine whether cigarette smokers display error-processing deficits as measured using error-related negativity (ERN) and error positivity (Pe). ERPs during an Eriksen flanker task were recorded from smokers and a non-smoking control group. Smokers showed the same ERN response as controls after making an error. However, the later Pe response was reduced as compared to the control group. On the behavioral level, we observed a trend towards increased error rates of smokers on incongruent trials. The present findings reveal that cigarette smoking is associated with reduced error processing. More specifically, while initial error processing seem intact, brain systems reflecting the motivational significance of a performance error seem compromised. It is argued that these cognitive deficits may cause or contribute to the persistence of smoking behavior and addictive behaviors in general. (c) 2009 Elsevier Ireland Ltd. All rights reserved