Interactive effects of contextual cues and acute alcohol intoxication on the associations between alcohol expectancy activation and urge to drink.
Interactive effects of contextual cues and acute alcohol intoxication on the associations between alcohol expectancy activation and urge to drink.
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情境线索和急性酒精中毒对酒精预期激活和饮酒冲动之间关联的交互作用。
DOI：
10.1037/a0037606
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发表时间：
2014
影响因子：
2.3
通讯作者：
Read,JenniferP
中科院分区：
文献类型：
--
作者：
Wardell,JeffreyD;Read,JenniferP
本研究考察了情境线索和酒精中毒对记忆中积极和消极酒精预期的激活与实验室酒精管理后自我报告的饮酒冲动之间的关联的联合影响。酗酒的年轻人被随机分配喝中等剂量的酒精或安慰剂（酒精操纵），然后听积极或消极的饮酒情景（线索操纵）。在这些操作之前和之后，参与者完成了一项酒精预期Stroop任务，评估积极和消极的预期激活，以及对饮酒冲动的自我报告。回归分析显示，酒精和提示操作对预期激活和提示后饮酒冲动变化之间的关联有共同的、缓和的影响。具体来说，消极期望激活的增加和积极期望激活的减少都预示着饮酒冲动的减少，但这仅适用于处于消极线索条件下的醉酒参与者。对于那些处于积极线索条件下的人来说，无论饮料条件如何，期望激活和饮酒冲动之间没有联系。结果表明，酒精预期的记忆激活是否对饮酒后的饮酒冲动有影响，可能取决于激活的预期与当前饮酒环境的相关性。这一过程似乎受到环境中上下文线索和酒精药理作用之间复杂的相互作用的影响。
This study examined the joint effects of contextual cues and alcohol intoxication on the associations between activation of positive and negative alcohol expectancies in memory and self-reported urges to drink alcohol after a laboratory alcohol administration. Young adult heavy drinkers were randomly assigned to drink a moderate dose of alcohol or a placebo (alcohol manipulation), and then listened to positive or negative drinking scenarios (cue manipulation). Before and after these manipulations, participants completed an alcohol expectancy Stroop task assessing positive and negative expectancy activation, as well as self-report measures of urges to drink. Regression analyses revealed that the alcohol and cue manipulations had a joint, moderating impact on the associations between expectancy activation and postcue changes in urge to drink. Specifically, both increased activation of negative expectancies and decreased activation of positive expectancies predicted decreases in urges to drink, but only for intoxicated participants in the negative cue condition. There were no associations between expectancy activation and urges to drink for those in the positive cue condition regardless of beverage condition. Results suggest that whether memory activation of alcohol expectancies has an impact on urge to drink after alcohol is on board may depend on the relevance of the activated expectancies to the current drinking context. This process appears to be influenced by a complex interaction between contextual cues in the environment and the pharmacological effects of alcohol.