Enteroendocrine cells in gastrointestinal pathophysiology
Enteroendocrine cells in gastrointestinal pathophysiology
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DOI：
10.1016/j.coph.2013.09.012
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发表时间：
2013-12-01
影响因子：
4
通讯作者：
McLaughlin, John T.
中科院分区：
文献类型：
--
作者：
Harrison, Elizabeth;Lal, Simon;McLaughlin, John T.
胃肠道中的肠内分泌细胞通过分泌肽在调节食欲和消化反应中发挥重要作用。它们与胃肠道疾病的参与已被承认，但相对较少的研究试图明确它们在发病机制中的作用或作为治疗靶点。最近但仍然有限的工作确定了 EEC 在胃肠道疾病中的新作用。
Enteroendocrine cells in the gastrointestinal tract play an important role in the regulation of appetite and digestive responses through the secretion of peptides. Their involvement in gastrointestinal diseases has been acknowledged, but relatively few studies have sought to clearly define their role in the pathogenesis or as therapeutic targets. Recent, but still limited, work has identified new roles for EEC in GI diseases.