Prevalence and prognostic importance of lung ultrasound findings in acute coronary syndrome: A systematic review.

Prevalence and prognostic importance of lung ultrasound findings in acute coronary syndrome: A systematic review.
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DOI:
10.1111/echo.15262
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发表时间:
2021-12
期刊:
Echocardiography (Mount Kisco, N.Y.)
影响因子:
--
通讯作者:
Platz E
Platz E
中科院分区:
其他
文献类型:
--
作者:
Lindner M;Lindsey A;Bain PA;Platz E

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心力衰竭(HF)并发急性冠状动脉综合征(ACS)是不良预后的一个先兆。在这项系统综述中,我们研究了肺超声(LUS)检查结果在ACS患者中的患病率及其预后价值。 我们在PubMed、EMBASE和Web of Science在线数据库中检索了在成年ACS患者[ST段抬高型心肌梗死(STEMI)、非ST段抬高型心肌梗死(NSTEMI)和不稳定型心绞痛]中使用LUS的研究(英文发表的全文文章)。 在筛选的462项研究中,2010年至2021年间发表的5项前瞻性观察性研究符合我们的纳入标准,共包括1087名患者。两项研究采用28分区成像方案,三项研究采用8分区方案。在所有研究中,既往有心力衰竭诊断的患者比例≤5%。在冠状动脉造影之前或之后12小时内检查了B线的患病率,由于成像方案或量化方法不同,不同研究的报告结果存在差异。入院时B线数量较多与基线住院期间发生有症状心力衰竭的风险增加以及采用8分区或28分区方案时住院期间死亡率较高有关。基线时B线数量较多也与随后因心力衰竭住院或全因死亡的风险增加有关。 入院时进行的LUS检查显示的肺淤血似乎是ACS住院患者中的常见表现,并且与不良的住院期间和长期预后相关。有必要使用标准化的LUS方案进行进一步研究,这有可能改善ACS的风险分层。
Heart failure (HF) complicating acute coronary syndrome (ACS) is a herald of adverse outcomes. In this systematic review, we investigated the prevalence of lung ultrasound (LUS) findings and their prognostic utility among patients with ACS. We searched the online databases PubMed, EMBASE, and Web of Science for studies (full-text articles, published in English) that used LUS in adult patients with ACS [ST-elevation myocardial infarction (STEMI), non-ST-elevation myocardial infarction (NSTEMI), and unstable angina]. Of 462 studies screened, five prospective, observational investigations published between 2010 and 2021 including 1087 patients met our inclusion criteria. Two studies employed 28-zone imaging protocols whereas three used eight-zone protocols. The proportion of patients with a prior HF diagnosis was ≤ 5% in all studies. The prevalence of B-lines was examined prior to or within 12 hours after coronary angiogram and reporting varied between studies due to different imaging protocols or quantification methods. A higher number of B-lines on admission was associated with an increased risk for developing symptomatic HF during the baseline hospitalization and with a higher in-hospital mortality rate using either 8 or 28-zone protocols. A higher number of B-lines at baseline was also associated with an increased risk of subsequent HF hospitalization or all-cause death. Pulmonary congestion by LUS performed on admission appears to be a common finding among patients hospitalized for ACS and is associated with adverse in-hospital and long-term outcomes. Further investigations using standardized LUS protocols are warranted and have the potential to improve risk stratification in ACS.
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