Nickel(II)-aryl complexes as catalysts for the Suzuki cross-coupling reaction of chloroarenes and arylboronic acids
Nickel(II)-aryl complexes as catalysts for the Suzuki cross-coupling reaction of chloroarenes and arylboronic acids
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DOI：
10.1016/j.tetlet.2007.01.175
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发表时间：
2007-03-26
影响因子：
1.8
通讯作者：
Yang, Lian-Ming
中科院分区：
文献类型：
--
作者：
Chen, Chen;Yang, Lian-Ming
一系列空气和水分稳定的Ni（II）-（σ-芳基）配合物Ni（PPh 3）（2）（aryl）X（X = Cl，Br）被用作Ni催化的Suzuki交叉偶联反应的催化剂前体。这些预催化剂容易原位形成催化活性Ni（0）物质，而不需要额外的还原剂。在温和的条件下（在60 ℃下，在THF中，以K2 CO 3为碱），Ni（PPh 3）（2）（1-naph）Cl和PPh 3组成的通用催化体系对芳基氯的Suzuki反应非常有效。(c)2007爱思唯尔有限公司保留所有权利。
A series of air- and moisture-stable Ni(II)-(sigma-aryl) complexes, Ni(PPh3)(2)(aryl)X (X = Cl, Br), were employed as catalyst precursors in the Ni-catalyzed Suzuki cross-coupling reaction. These pre-catalysts easily form the catalytically active Ni(0) species in situ without the need of additional reducing agents. A general catalytic system involving Ni(PPh3)(2)(1-naph)Cl and PPh3 proved to be highly effective for the Suzuki reaction of aryl chlorides under mild conditions (at 60 degrees C in THF in the presence of K2CO3 as the base). (c) 2007 Elsevier Ltd. All rights reserved.