Isolation of constituents and anti-complement activity fromAcer okamotoanum
Isolation of constituents and anti-complement activity fromAcer okamotoanum
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冈本枫的成分分离和抗补体活性
DOI：
10.1007/bf02977691
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发表时间：
2007
影响因子：
6.7
通讯作者：
K. Bae
中科院分区：
文献类型：
--
作者：
W. Jin;B. Min;Jongpill Lee;P. Thuong;Hyeong;K. Song;Y. Seong;K. Bae
从冈本茂槭（Acer okamotopentudi Nakai）的叶和枝中分离得到一个新的酰基甾醇葡萄糖苷（1）沿着分离得到4个已知化合物：β-香树脂醇乙酸酯（2），3β，24-二羟基蒲公英-14-烯（3），cleomiscosin A（4）和deomiscosin C（5）。通过化学分析和光谱分析，确定新化合物的结构为β-谷甾醇葡萄糖苷-3 '-0-二十六烷酸酯。此外，发现新化合物对经典途径激活的补体系统表现出显著的抑制作用（IC 50值为0.2（μM））。
A novel acylated sterol glucoside (1) along with four known compounds, β-amyrin acetate (2), 3β,24-dihydroxytaraxer-14-ene (3), cleomiscosin A (4), and deomiscosin C (5), were isolated from the leaf and twig ofAcer okamotoanumNakai (Aceraceae). The structure of the new compound was determined to be β-sitosterol glucoside-3’-0-hexacosanoicate based on chemical and spectroscopic analyses. In addition, the novel compound was found to exhibit a significant inhibitory effect (IC50value of 0.2 (μM) on the complement system activated by the classical pathway.