Gold(I)-Catalyzed Activation of Alkynes for the Construction of Molecular Complexity.
Gold(I)-Catalyzed Activation of Alkynes for the Construction of Molecular Complexity.
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DOI：
10.1021/cr500691k
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发表时间：
2015-09-09
期刊：
影响因子：
62.1
通讯作者：
Echavarren AM
中科院分区：
文献类型：
--
作者：
Dorel R;Echavarren AM
几个世纪以来，黄金一直被认为是一种贵重的、纯粹是装饰性的惰性金属。直到1986年，Ito和Hayashi才描述了金(I)在均相催化中的第一个应用。1十多年后，Teles 2和Tanaka报道了金(I)活化炔烃的第一个例子，3揭示了金(I)在有机合成中的潜力。目前，金(I)络合物是均相条件下烯烃亲电活化最有效的催化剂，具有广泛的用途。
For centuries, gold had been considered a precious, purely decorative inert metal. It was not until 1986 that Ito and Hayashi described the first application of gold (I) in homogeneous catalysis. 1 More than one decade later, the first examples of gold (I) activation of alkynes were reported by Teles 2 and Tanaka, 3 revealing the potential of gold (I) in organic synthesis. Now, gold (I) complexes are the most effective catalysts for the electrophilic activation of alkynes under homogeneous conditions, and a broad range of versatile