The risk of large for gestational age across increasing categories of pregnancy glycemia.
The risk of large for gestational age across increasing categories of pregnancy glycemia.
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DOI:
10.1016/j.ajog.2010.10.907
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发表时间:
2011-03
影响因子:
9.8
通讯作者:
Ferrara A
中科院分区:
文献类型:
--
作者:
Ehrlich SF;Crites YM;Hedderson MM;Darbinian JA;Ferrara A
To estimate the risk of large for gestational age (LGA) across categories of glucose tolerance. In a cohort of 89,141, women without GDM were categorized by their screening and diagnostic test results, those with GDM were categorized as meeting the NDDG or only the ADA criteria. Multivariable logistic regression models estimated the risk of LGA; screening values 5.5–6.0 mmol/L comprised the referent. In women without GDM, the OR for LGA was 1.89 (95% CI 1.45–2.45) for fasting, 1.57 (95% CI 1.31–1.89) for 1-hr, 1.60 (95% CI 1.33–1.93) for 2-hr and 1.62 (95% CI 1.23–2.14) for 3-hr values meeting the ADA time-point specific thresholds. For GDM identified in a two-step procedure, our findings support the use of isolated abnormal fasting values according to the ADA threshold in identifying women who could benefit from treatment.
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