The effect of radiotherapy on rectal cancer: a histopathological appraisal and prognostic indicators.
The effect of radiotherapy on rectal cancer: a histopathological appraisal and prognostic indicators.
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DOI：
10.3857/roj.2020.00010
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发表时间：
2020-06
影响因子：
2.3
通讯作者：
Haboubi N
中科院分区：
文献类型：
--
作者：
AlQudah M;Salmo E;Haboubi N
直肠癌的治疗是一项重要的工作。目前有多种治疗方式，并发症程度各不相同。放射治疗（RT）是最常用的方式之一，无论是单独使用还是更频繁地与化疗一起使用，主要是在最终手术之前。RT的结果是不可预测的。RT有严重的副作用，并且不能保证它对所有患者都有效。本文概述了RT对肿瘤的影响，回顾了RT反应的各种分期系统，并提出了最近的证据表明，哪些情况下对这种治疗反应较低，以避免不必要的并发症。
The management of rectal cancer is a major undertaking. There are currently multiple treatment modalities with variable degrees of complications. Radiotherapy (RT) is one of the more frequently used modalities either on its own or more frequently with chemotherapy mostly before the definitive surgery. The outcome of RT is unpredictable. RT has its serious side effects and there are no guarantees of its usefulness in all patients. This article outlines the effect of RT on the tumor, reviews the various staging systems of responses to RT and present recent evidence of which case is less responsive to such treatments to avoid unnecessary complications.