Performance of a direct LDL-cholesterol method compared to beta quantification
Performance of a direct LDL-cholesterol method compared to beta quantification
复制标题
DOI：
10.1351/pac199668101887
复制
发表时间：
1996-10-01
影响因子：
1.8
通讯作者：
Gebski, CP
中科院分区：
文献类型：
--
作者：
Pisani, T;Pickering, S;Gebski, CP
低密度脂蛋白胆固醇目前由临床实验室使用弗里德瓦尔德公式估计，该公式需要空腹标本，并且随着甘油三酯水平的增加而受到误差的影响。我们描述了一种快速分离低密度脂蛋白的方法，通过免疫分离，随后通过酶法测定胆固醇。Direct LDL（TM）免疫分离试剂符合当前的精密度指南，其批内和批间变异系数为
Low-density lipoprotein cholesterol is currently estimated by clinical laboratories using the Friedewald formula which requires fasting specimens and is subject to error with increasing triglyceride levels. We describe a rapid method for isolating low-density lipoproteins by immunoseparation for subsequent measurement of cholesterol by enzymatic assay. The Direct LDL(TM) Immunoseparation Reagent meets current guidelines for precision with intra-assay and interassay coefficients of variation of