Patterns of glaucomatous visual field progression identified by three progression criteria
Patterns of glaucomatous visual field progression identified by three progression criteria
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DOI：
10.1016/j.ajo.2004.07.003
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发表时间：
2004-12-01
影响因子：
4.2
通讯作者：
Sample, PA
中科院分区：
文献类型：
--
作者：
Boden, C;Blumenthal, EZ;Sample, PA
目的：确定可重复青光眼视野进展的典型模式。设计：回顾性分析两项前瞻性研究的数据。方法：纳入72例患者的72只眼睛，在2年内检测了6次，40例患者的40只眼睛每年随访12年。每位患者均有两个基线视野异常、视神经异常和系列视野异常。通过三种方法确定进展：青光眼改变概率（使用总偏差（GCP-TD）和模式偏差（GCP-PD）图）和临床标准。进展分为现有暗斑的加深或扩大，或新的暗斑。结果：重复进展的眼睛比例为17% ~ 27%。在年度组中，最常见的进展模式是现有暗斑的加深，其次是扩大。需要两次随访，加深的百分比仅为20%（临床分类器）。扩展和深化的组合是最常见的GCP标准：15% （GCP- td分类器）和10% （GCP- pd分类器）为年度组。对于半年一次的组，临床标准中加深最常见（11%的眼睛），GCP标准中加深伴扩张最常见（14%，GCP- td和GCP- pd）。没有眼睛出现可重复的新暗点。结论：青光眼的视野在基线测试显示存在暗斑的视野区域进展。后续测试可以通过集中在已经有缺陷的位置，在视野的正常区域使用更稀疏的测试模式或筛选算法来改进。(C) 2004年Elsevier Inc.版权所有。
PURPOSE: To determine typical patterns of repeatable glaucomatous visual field progression.DESIGN: Retrospective analysis of data obtained from two prospective studies.METHODS: Included were 72 eyes of 72 patients tested up to six times over 2 years, and 40 eyes of 40 patients followed annually for up to 12 years. Each patient had two abnormal baseline visual fields, abnormal optic nerves, and serial fields. Progression was identified using three methods: by glaucoma change probability using total deviation (GCP-TD) and pattern deviation (GCP-PD) plots and by a clinical criteria. Progression was categorized as deepening or expansion of an existing scotoma, or a new scotoma.RESULTS: The percentage of eyes repeatably progressed ranged from 17% to 27%. The most common pattern of progression was a deepening of an existing scotoma in the annual group, followed by expansion. With two follow, ups required, percentages for deepening only were 20% (clinical classifier). A combination of expansion and deepening was most common for the GCP criteria: 15% (GCP-TD classifier), and 10% (GCP-PD classifier) for the annual group. For the semiannual group, deepening was most common with the clinical criteria (11% of eyes), and deepening with expansion was most common by GCP criteria (14%, GCP-TD and GCP-PD). No eyes showed repeatable new scotomas.CONCLUSIONS: Glaucomatous visual fields progress in the area of the visual field where baseline testing showed an existing scotoma. Follow-up testing might be improved by concentrating on already defective locations and using sparser test patterns or screening algorithms in normal areas of the visual field. (C) 2004 by Elsevier Inc. All rights reserved.