Sexual problems of diabetic men.
Sexual problems of diabetic men.
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糖尿病男性的性问题。
DOI：
10.1136/bmj.285.6346.911
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发表时间：
1982
期刊：
影响因子：
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通讯作者：
R. Tattersall
中科院分区：
文献类型：
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作者：
R. Tattersall
那么，我们为什么不使用灭活脊髓灰质炎疫苗作为儿童的常规免疫接种呢？父母不需要与孩子同时接种;目前的灭活脊髓灰质炎疫苗（与最早的例子相比有了很大改进）可以产生可靠和持久的免疫力，并且是安全的。此外，在荷兰，疫苗实际上已经消灭了这种疾病，9除了某些反对疫苗接种的宗教团体。答案在于我们相对较低的脊髓灰质炎疫苗接种率。目前，平均只有大约80%的婴儿完成了一个疗程的减毒活口服疫苗;要在全国范围内有效，灭活脊髓灰质炎疫苗可能需要达到北方欧洲达到的9000多人的高水平。这就是我们在脊髓灰质炎疫苗接种方面的困境：除非我们能够大幅提高儿童的常规免疫接种率，否则我们将不得不继续坚持口服减毒活疫苗，这在英国非常成功，并接受偶尔与疫苗相关的麻痹性脊髓灰质炎病例。
Why do we not, then, use inactivated polio vaccines for routine immunisation in childhood? Parents would not need to be immunised at the same time as their child; and the current inactivated polio vaccines (improved considerably compared with the earliest examples) induce reliable and lasting immunity and are safe. Moreover, in the Netherlands the vaccine has virtually eliminated the disease,9 except in certain antivaccine religious groups. The answer lies in our relatively poor uptake rates for polio vaccine. At present only about 80% of infants, on average, complete a course of live attenuated oral vaccine; and to be effective nationally, inactivated polio vaccine probably needs the high levels of more than 9000 achieved in northern Europe. Therein lies our dilemma with polio vaccination: unless we can increase routine immunisation rates in childhood substantially, we will have to continue to persevere with live attenuated oral vaccine, which has been highly successful in Britain, and to accept the occasional case of vaccine-associated paralytic poliomyelitis that goes with it. NORMAN D NOAH