A case of Lhermitte-Duclos disease presenting high FDG uptake on FDG-PET/CT

A case of Lhermitte-Duclos disease presenting high FDG uptake on FDG-PET/CT
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DOI:
10.1007/s11060-007-9355-x
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发表时间:
2007-09-01
影响因子:
3.9
通讯作者:
Takeda, Kan
Takeda, Kan
中科院分区:
医学2区
文献类型:
--
作者:
Nakagawa, Toshio;Maeda, Masayuki;Takeda, Kan

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Lhermitte-Duclos Disease (LDD) is a rare cerebellar lesion that has long been controversial as to whether the entity is a hamartoma, a malformation, or a neoplasm. Recent advances in metabolic imaging and molecular biology have unveiled biological features of LDD and a close relationship between LDD and Cowden disease. Adult onset LDD is now considered identical to Cowden disease in a US guideline. We present a case of LDD, in which high fluorodeoxy glucose (FDG) uptake was shown on PET/CT. We performed dual time point scans, in which a delayed scan exhibited more intense FDG uptake by the hamartomatous lesion than an early scan. We must remain aware of the possibility of LDD when intense accumulation is observed in a cerebellar lesion on FDG-PET/CT imaging.