SUBSTANTIA NIGRA DOPAMINE NEURONS - SEPARATE POPULATIONS PROJECT TO NEOSTRIATUM AND ALLOCORTEX

SUBSTANTIA NIGRA DOPAMINE NEURONS - SEPARATE POPULATIONS PROJECT TO NEOSTRIATUM AND ALLOCORTEX
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DOI:
10.1016/0304-3940(78)90160-x
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发表时间:
1978-01-01
影响因子:
2.5
通讯作者:
MOORE, RY
MOORE, RY
中科院分区:
医学4区
文献类型:
--
作者:
FALLON, JH;RILEY, JN;MOORE, RY

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用荧光组织化学、高尔基体法和辣根过氧化物酶逆行追踪法对大鼠黑质多巴胺(DA)神经元进行了分析,结果表明存在2种不同的神经元群。位于黑质背侧的DA神经元具有水平定向的树突,并且主要投射到基底前脑的异皮质区域。位于脑内的DA神经元有树突延伸到网状部,主要投射到新纹状体。黑质DA能神经元在解剖学和功能上应被视为两个独立的组。
Analysis of the dopamine (DA) neurons of the rat substantia nigra, pars compacta using fluorescence histochemistry, the Golgi method and retrograde transport of horseradish peroxidase indicates the presence of 2 distinct populations of neurons. DA neurons located dorsally in the nigra have horizontally oriented dendrites and project principally to allocortical regions of the basal forebrain. Ventrally located DA neurons have dendrites extending into pars reticulata and project principally to neostriatum. The nigral DA neurons should be viewed as 2 separate groups, both anatomically and functionally.