Reliability, Validity, and Factor Structure of the Hopkins Symptom Checklist-25: Population-Based Study of Persons Living with HIV in Rural Uganda
Reliability, Validity, and Factor Structure of the Hopkins Symptom Checklist-25: Population-Based Study of Persons Living with HIV in Rural Uganda
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DOI：
10.1007/s10461-017-1843-1
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发表时间：
2018-05-01
影响因子：
4.4
通讯作者：
Tsai, Alexander C.
中科院分区：
文献类型：
--
作者：
Ashaba, Scholastic;Kakuhikire, Bernard;Tsai, Alexander C.
抑郁症和焦虑症在艾滋病毒感染者 (PLHIV) 中高度共存，但很少有筛查或测量仪器经过验证可在撒哈拉以南非洲使用。本研究的目的是确定乌干达农村地区 PLHIV 人群样本中 25 项霍普金斯症状检查表 (HSCL) 的可靠性、有效性和因素结构。 This study was nested within an ongoing population-based cohort of all residents living in Nyakabare Parish, Mbarara District, Uganda. All participants who identified as HIV-positive by self-report were included in this analysis. We performed parallel analysis on the scale items and estimated the internal consistency of the identified sub-scales using ordinal alpha.为了评估构建有效性，我们将子量表与相关构建相关联，包括主观幸福感（幸福）、粮食不安全和健康状况。 Of 1814 eligible adults in the population, 158 (8.7%) self-reported being HIV positive.平均年龄为 41 岁，其中 68% 为女性。 Mean HSCL-25 scores were higher among women compared with men (1.71 vs. 1.44; t = 3.6, P < 0.001).平行分析揭示了一个三因素结构，可以解释 83% 的差异：抑郁（7 项）、焦虑（5 项）和躯体症状（7 项）。 The ordinal alpha statistics for the sub-scales ranged from 0.83 to 0.91. Depending on the sub-scale, between 27 and 41% of the sample met criteria for caseness.子量表分数与幸福感、粮食不安全和自我报告的整体健康状况之间的估计相关性显示了结构效度的有力证据。 The HSCL-25 is a reliable and valid measure of mental health among PLHIV in rural Uganda.在筛查抑郁症症状时通常会引起躯体症状的文化背景下，将躯体项目从针对艾滋病毒感染者的抑郁症状检查表中排除可能是不可取的。
Depression and anxiety are highly comorbid among people living with HIV (PLHIV), but few instruments for screening or measurement have been validated for use in sub-Saharan Africa. The objective of this study was to determine the reliability, validity, and factor structure of the 25-item Hopkins Symptom Checklist (HSCL) in a population-based sample of PLHIV in rural Uganda. This study was nested within an ongoing population-based cohort of all residents living in Nyakabare Parish, Mbarara District, Uganda. All participants who identified as HIV-positive by self-report were included in this analysis. We performed parallel analysis on the scale items and estimated the internal consistency of the identified sub-scales using ordinal alpha. To assess construct validity we correlated the sub-scales with related constructs, including subjective well being (happiness), food insecurity, and health status. Of 1814 eligible adults in the population, 158 (8.7%) self-reported being HIV positive. The mean age was 41 years, and 68% were women. Mean HSCL-25 scores were higher among women compared with men (1.71 vs. 1.44; t = 3.6, P < 0.001). Parallel analysis revealed a three-factor structure that explained 83% of the variance: depression (7 items), anxiety (5 items), and somatic symptoms (7 items). The ordinal alpha statistics for the sub-scales ranged from 0.83 to 0.91. Depending on the sub-scale, between 27 and 41% of the sample met criteria for caseness. Strong evidence of construct validity was shown in the estimated correlations between sub-scale scores and happiness, food insecurity, and self-reported overall health. The HSCL-25 is a reliable and valid measure of mental health among PLHIV in rural Uganda. In cultural contexts where somatic complaints are commonly elicited when screening for symptoms of depression, it may be undesirable to exclude somatic items from depression symptom checklists administered to PLHIV.