Complete hydatidiform mole in a triplet pregnancy coexisting two viable fetuses: Case report and review of the literature
Complete hydatidiform mole in a triplet pregnancy coexisting two viable fetuses: Case report and review of the literature
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DOI：
10.1046/j.1341-8076.2003.00124.x
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发表时间：
2003-10-01
影响因子：
1.6
通讯作者：
Saito, S
中科院分区：
文献类型：
--
作者：
Takagi, K;Unno, N;Saito, S
我们报告一例罕见的完全性葡萄胎合并两个或两个以上胎儿同时存在，两个胎儿均存活且无并发症。一名男婴体重1258 g，一名女婴体重880 g，分娩时无并发症，出生后95天出院。DNA微卫星多态性分析表明，该痣是父亲的起源，可能是纯合子。母亲患有多发性肺转移的葡萄胎，这是发现手术后3天，并成功地治疗了甲氨蝶呤。一个完整的葡萄胎有两个或多个胎儿共存，产生了立即终止妊娠和继续妊娠之间的困境。虽然目前的情况下，在一个有利的结果，审查14例报告的情况下，高胎儿丢失率（90%）必须考虑在决定管理这样的妊娠。
We report a rare case of a complete hydatidiform mole with two or more coexisting fetuses where both infants survived without complications. A male infant weighing 1258 g and a female infant weighing 880 g were delivered without complications and discharged 95 days after the birth. The analysis of DNA microsatellite polymorphisms indicated that the mole was of paternal origin and probably homozygous. The mother suffered from multiple pulmonary metastasis of the hydatidiform mole which was detected 3 days after the surgery and was successfully treated with methotrexate. A complete hydatidiform mole with two or more coexisting fetuses produces a dilemma between immediate termination and pregnancy continuation. Although the present case resulted in a favorable outcome, a review of the 14 reported cases suggests that the high fetal loss rate (90%) must be a consideration in the decision regarding management of such a pregnancy.