CONTROL OF GRANULOCYTES AND MACROPHAGES - MOLECULAR, CELLULAR, AND CLINICAL ASPECTS
CONTROL OF GRANULOCYTES AND MACROPHAGES - MOLECULAR, CELLULAR, AND CLINICAL ASPECTS
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DOI：
10.1126/science.1948028
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发表时间：
1991-10-25
期刊：
影响因子：
56.9
通讯作者：
METCALF, D
中科院分区：
文献类型：
--
作者：
METCALF, D
粒细胞和巨噬细胞这两种重要白细胞的产生和功能活性主要受一组糖蛋白集落刺激因子的调节。集落刺激因子已通过重组技术大量生产，现已证明在预防或抑制各种血细胞形成不正常或有缺陷的个体的感染方面具有价值。
The production and functional activity of two important white blood cells, the granulocytes and macrophages, are regulated mainly by a group of glycoprotein colony-stimulating factors. The colony-stimulating factors have been mass-produced with recombinant technology and are now proving of value in preventing or suppressing infections in a variety of individuals with subnormal or defective formation of blood cells.