Reproduction of Myxoviruses
Reproduction of Myxoviruses
复制标题
粘病毒的繁殖
DOI：
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发表时间：
1975
期刊：
影响因子：
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通讯作者：
P. Choppin
中科院分区：
文献类型：
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作者：
R. Compans;P. Choppin
粘病毒组由人和动物的流感病毒组成。最初建议指定（Andrewes等人，1955）对一组对某些粘液物质表现出亲和性的病毒，除流感病毒外，还包括腮腺炎和纽卡斯尔病病毒（NDV）。后来人们认识到，前两种病毒应被分成一个不同的组，因为它们与流感病毒之间在结构和复制方面存在许多差异（Waterson，1962），术语副粘病毒已被用于包括这些因子的组。因此，目前构成的粘病毒组（有时称为正粘病毒; Melnick，1973）仅包含流感病毒。如第2节所述，在流感病毒粒子的多肽中，有两种不同的具有血凝素和神经氨酸酶活性的表面多肽和一种内部核糖核蛋白（RNP）。这些多肽的抗原性为流感病毒的类型、亚型和毒株的分类提供了基础。表1显示了分类系统，并列出了一些常用的菌株。
The myxovirus group consists of the influenza viruses of man and animals. The designation was originally suggested (Andrewes et al., 1955) for a group of viruses which exhibited affinity for certain mucoid substances, and included mumps and Newcastle disease viruses (NDV) in addition to influenza viruses. It was recognized subsequently that the former two viruses should be separated into a distinct group because of numerous differences in structure and replication between them and the influenza viruses (Waterson, 1962), and the term paramyxovirus has been adopted for the group which includes these agents. Thus, the myxovirus group (sometimes referred to as orthomyxoviruses; Melnick, 1973) as presently constituted contains only the influenza viruses. As described in sect. 2, among the polypeptides of the influenza virion are two distinct surface polypeptides with hemagglutinin and neuraminidase activities and an internal ribonucleoprotein (RNP). The antigenicity of these polypeptides has provided a basis for the classification of influenza viruses into types, subtypes, and strains. Table 1 indicates the system of classification and lists some of the strains in common use.