A NUCLEUS IN THE DORSOLATERAL FUNICULUS OF THE SPINAL CORD OF THE RAT
A NUCLEUS IN THE DORSOLATERAL FUNICULUS OF THE SPINAL CORD OF THE RAT
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DOI：
10.1016/0006-8993(68)90204-7
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发表时间：
1968-01-01
期刊：
影响因子：
2.9
通讯作者：
WALDRON H A
中科院分区：
文献类型：
--
作者：
GWYN D G;WALDRON H A
对大鼠脊髓中乙酰胆碱酯酶分布的研究表明，背外侧索中有一组细胞显示出不同程度的酶活性。在脊髓的颈段，这群细胞占据的位置与其他物种的外侧颈核相似。然而，在大鼠中，发现核延伸遍及脊髓的整个长度，从脊髓髓交界处到骶段。在胆碱酯酶制备中，核内的一些细胞位于背角的最外侧尖端的腹外侧，而其他细胞则位于背角基部附近的内侧。细胞核内的主要细胞群位于这两个极端之间。细胞核中的大多数细胞是多极的，尺寸为8-36 μ乘4-12 μ。许多细胞突起在内侧方向上朝向位于背角基部的一组细胞，尽管少数细胞突起在头尾方向上行进。核内许多细胞的高水平乙酰胆碱酯酶活性可能表明它们是胆碱能的。硫堇染色标本证实，该核伸展于脊髓的全长，提示大鼠的该核可能具有与其他物种的颈外侧核相似的功能，它可以接受脊髓各节段的传入纤维。
Investigations of the distribution of acetylcholinesterase in the spinal cord of the rat have revealed a group of cells in the dorsolateral funiculus which show varying degrees of enzyme activity. In cervical segments of the spinal cord this group of cells occupies a pposition similar to that described for the lateral cervical nucleus in other species. However, in the rat the nucleus is found to extend throughout the whole length of the cord, from the spinomedullary junction to sacral segments.In cholinesterase preparations some cells within the nucleus are located ventrolateral to the extreme lateral tip of the dorsal horn, while other cells are observed more medially near the base of the dorsal horn. The main group of cells within the nucleus lies between these two extremes. Most of the cells in the nucleus are multipolar and have dimensions of 8–36 μ by 4–12 μ. Many of the cell processes pass in a medial direction towards a group of cells located at the base of the dorsal horn, although a few cell processes run in a cranio-caudal direction. The high level of acetylcholinesterase activity in many cells in the nucleus may indicate that they are cholinergic. Thionin stained preparations confirm that the nucleus extends throughout the whole length of the spinal cord.It is suggested that this nucleus in the rat may have a function similar to the lateral cervical nucleus of other species, and that it may receive afferent fibres at all segmental levels.