spolTools: online utilities for analyzing spoligotypes of the Mycobacterium tuberculosis complex
spolTools: online utilities for analyzing spoligotypes of the Mycobacterium tuberculosis complex
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DOI：
10.1093/bioinformatics/btn434
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发表时间：
2008-10-15
期刊：
影响因子：
5.8
通讯作者：
Tanaka, Mark M.
中科院分区：
文献类型：
--
作者：
Tang, Chaka;Reyes, Josephine F.;Tanaka, Mark M.
spolTools是一个在线程序的集合，旨在操作和分析结核分枝杆菌复合体的spoligotype数据集。这些工具被集成到一个存储库中，目前包含1179个spoligotypes和6278个分离株在30个数据集。用户可以搜索此数据库以导出供外部使用或传递到集成工具。这些工具包括计算基本群体遗传量，基于估计的进化历史的spoligotype模式簇的可视化和预测新出现的菌株的程序-与传播增加相关的基因型。
spolTools is a collection of online programs designed to manipulate and analyze spoligotype datasets of the Mycobacterium tuberculosis complex. These tools are integrated into a repository currently containing 1179 spoligotypes and 6278 isolates across 30 datasets. Users can search this database to export for external use or to pass on to the integrated tools. These tools include the computation of basic population genetic quantities, the visualization of clusters of spoligotype patterns based on an estimated evolutionary history and a procedure to predict emerging strains - genotypes associated with elevated transmission.