Interaction between cardiac beat-to-beat interval changes an systolic blood pressure changes
Interaction between cardiac beat-to-beat interval changes an systolic blood pressure changes
复制标题
DOI：
10.1007/s10286-004-0169-z
复制
发表时间：
2004-04-01
影响因子：
5.8
通讯作者：
Murray, A
中科院分区：
文献类型：
--
作者：
Bowers, EJ;Murray, A
本研究评估了心跳间隔变化与收缩压 (SP) 变化之间的相互作用。 20 名受试者按照每分钟 4、6、8、10、12 和 14 次呼吸的显示呼吸信号进行规律呼吸，每次呼吸持续 5 分钟。记录心电图、无创血压（Finapres）和呼吸波形。计算 RR 间隔和 SP 变化的循环模式之间的时间偏移。显示的呼吸信号得到很好的跟踪；显示和记录的呼吸信号之间的平均相关性范围为 0.72 至 0.86。 RR 间隔峰值和随后的 SP 波谷之间的时间偏移随着呼吸频率的增加而减少，3.8 +/- 1.7 s、3.5 +/- 0.7 s、3.1 +/- 0.6 s、2.6 +/- 0.4 s、2.3 +/- 0.4 s 和 2.0 +/- 0.4 s 平均值+/- SD每分钟分别为 4、6、8、10、12 和 14 次呼吸。平均时间偏移和频率之间的关系显着 (p < 0.001)，95% 预测间隔为 +/-0.24 秒。已发表的数据显示时间偏移和频率之间没有关系，95% 的预测间隔为 +/- 2.8 秒。然而，当本研究中提出的偏移量定义应用于这些数据时，显着关系（p < 0.01）显而易见，95% 的预测间隔为 +/-1.5 s。总之，当应用标准化方法呈现结果时，先前明显矛盾的研究结果达成了良好的共识。 RR 间隔和血压变化之间存在延迟，并且该延迟随呼吸频率而变化。
This study assessed the interaction between cardiac beat-to-beat interval changes and systolic pressure (SP) changes. Twenty subjects breathed regularly following displayed breathing signals at 4, 6, 8, 10, 12 and 14 breaths per minute, each for 5 minutes. ECG, non-invasive blood pressure (Finapres) and respiration waveforms were recorded. Time offsets between the cyclic patterns of RR-interval and SP changes were calculated. Displayed breathing signals were well followed; the mean correlation between displayed and recorded breathing signals ranged from 0.72 to 0.86. The time offset between RR-interval peaks and subsequent SP troughs decreased with increasing respiration rate, 3.8 +/- 1.7 s, 3.5 +/- 0.7 s, 3.1 +/- 0.6 s, 2.6 +/- 0.4 s, 2.3 +/- 0.4 s and 2.0 +/- 0.4 s mean +/- SD at 4,6,8,10,12 and 14 breaths per minute respectively. The relationship between mean time offset and frequency was significant (p < 0.001), with a 95 % prediction interval of +/-0.24 s. Published data showed no relationship between time offset and frequency, with a 95% prediction interval of +/- 2.8 s. However, when the offset definition proposed in this research was applied to these data, a significant relationship (p < 0.01) was evident, with a 95% prediction interval of +/-1.5 s. In conclusion, apparently contradictory previous findings achieve good consensus when a standardized method for presenting results is applied. A delay exists between RR-interval and blood pressure changes, and this delay varies with breathing frequency.