CENTRAL AND PERIPHERAL CONTRAST SENSITIVITY IN AMBLYOPIA WITH VARYING FIELD SIZE

CENTRAL AND PERIPHERAL CONTRAST SENSITIVITY IN AMBLYOPIA WITH VARYING FIELD SIZE
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DOI:
10.1007/bf00679799
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发表时间:
1984-01-01
影响因子:
1.4
通讯作者:
BEDELL, HE
BEDELL, HE
中科院分区:
医学4区
文献类型:
--
作者:
KATZ, LM;LEVI, DM;BEDELL, HE

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0度、10度弱视视力下降的程度。和20度。视网膜偏心是通过测量正弦波栅对不同视野大小的对比敏感度来确定的。对比敏感度函数随刺激视野大小、视网膜位置和弱视程度而变化。弱视眼的峰值对比敏感度随着视野大小的增大而显著增加,达到与大视野非弱视对侧眼相同的程度。在外围,弱视眼的峰值对比敏感度在所有检查的视野大小中都保持较低的水平。在弱视眼中,所有视野大小的中心和外围的高空间频率截止都减少了。增加视野大小对截止敏感度的影响小于对峰值对比敏感度的影响。弱视缺陷,就峰值对比敏感度和敏锐度而言,可能并不局限于中心凹区域。在峰值对比度敏感度方面,弱视眼比非弱视眼更大程度地受益于刺激视野的增加。提出了一个模型,该模型表明,所获得的结果是由于自然发生弱视的人的弱视眼睛驱动的皮质神经元更少和/或更不敏感。
The extent of the amblyopic deficit at 0.degree., 10.degree. and 20.degree. retinal eccentricity was established using contrast sensitivity measures for sine wave gratings subtending various field sizes. Contrast sensitivity functions were shown to vary with stimulus field size, retinal location and degree of amblyopia. Foveally, peak contrast sensitivity of amblyopic eyes increased markedly with increasing field size, to reach the same magnitude as that of the contralateral nonamblyopic eyes for large fields. Peripherally, peak contrast sensitivity remained lower in the amblyopic eyes for all field sizes examined. High spatial frequency cut-offs were reduced both centrally and peripherally with all field sizes in the amblyopic eyes. The effect of increasing field size on the cut-off acuity was found to be smaller than the effect on peak contrast sensitivity. The amblyoptic deficit, in terms of both peak contrast sensitivity and acuity may not be restricted to the central foveal region. Amblyopic eyes benefit to a greater extent from increased stimulus field size than non amblyopic eyes in terms of peak contrast sensitivity. A model is proposed which suggests that the results obtained are due to fewer and/or less sensitive cortical neurons being driven by the amblyopic eye in humans with naturally occurring amblyopia.