Galaxy: a web-based genome analysis tool for experimentalists.
Galaxy: a web-based genome analysis tool for experimentalists.
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Galaxy：一种基于Web的基因组分析工具。
DOI：
10.1002/0471142727.mb1910s89
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发表时间：
2010-01
影响因子：
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通讯作者：
Taylor, James
中科院分区：
文献类型：
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作者：
Blankenberg, Daniel;Von Kuster, Gregory;Coraor, Nathaniel;Ananda, Guruprasad;Lazarus, Ross;Mangan, Mary;Nekrutenko, Anton;Taylor, James
高通量数据生产已经彻底改变了分子生物学。然而，数据生成能力的大规模增加需要更复杂的分析方法，并且通常非常计算密集。因此，理解高通量数据需要信息学的支持。Galaxy（galaxyproject.org）是一个软件系统，它通过一个框架提供这种支持，该框架为实验人员提供了强大工具的简单界面，同时自动管理计算细节。Galaxy既可以作为一个公开的网络服务，提供用于分析基因组、比较基因组和功能基因组数据的工具，也可以作为一个可下载的软件包，部署在各个实验室中。无论哪种方式，它都允许没有信息学或编程专业知识的实验人员仅用Web浏览器进行复杂的大规模分析。
High-throughput data production has revolutionized molecular biology. However, massive increases in data generation capacity require analysis approaches that are more sophisticated, and often very computationally intensive. Thus making sense of high-throughput data requires informatics support. Galaxy (http://galaxyproject.org) is a software system that provides this support through a framework that gives experimentalists simple interfaces to powerful tools, while automatically managing the computational details. Galaxy is available both as a publicly available web service, which provides tools for the analysis of genomic, comparative genomic, and functional genomic data, or a downloadable package that can be deployed in individual labs. Either way, it allows experimentalists without informatics or programming expertise to perform complex large-scale analysis with just a web browser.